Search for dissertations about: "mathematical cancer"
Showing result 1 - 5 of 51 swedish dissertations containing the words mathematical cancer.
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1. Utilization of single-cell RNA-Seq and genome-scale modeling for investigating cancer metabolism
Abstract : Cancer remains a leading cause of death worldwide, and its dysregulated metabolism is a promising target for therapy. However, metabolism is complex to study – the metabolism of a cell involves the interplay of thousands of chemical reactions that are combined in different ways across tissues and cell types. READ MORE
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2. Development of Computational Methods for Cancer Research: Strategies for closing the feedback loop in omics workflows
Abstract : As the ultimate workhorses of the living things, proteins undergo significant regulatory activity throughout the lifetime of a cell or an organism. Many complex diseases effect the protein composition, expression or modification in the cells or tissues they arise in. READ MORE
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3. Image analysis of prostate cancer tissue biomarkers
Abstract : Prostate cancer is the second most common cancer in men. In order to improve diagnosis and prognosis, new sensitive and specific biomarkers are needed. Tissue biomarkers carry expression and morphological information of the tissue where they are expressed. READ MORE
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4. Radiation Oncology Data and Modelling Side Effects after Radiation Therapy
Abstract : Although modern radiation therapy techniques have the ability to conform the dose distribution of ionizing radiation tightly around the volume to be treated, unwanted irradiation to surrounding organs remains a problem. The probability of a side effect arising in the normal tissue of a patient after radiation therapy can be modelled by sigmoid mathematical functions known as normal tissue complication probability (NTCP) models. READ MORE
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5. Nonlinear Mixed Effects Modeling of Combination Therapies in Oncology
Abstract : It has been shown that simultaneous administration of two or more anticancer agents can have a beneficial effect on cancer patients. This type of treatment is called combination therapy and is nowadays commonly used in the fight against cancer. READ MORE