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Showing result 1 - 5 of 8 swedish dissertations matching the above criteria.

2. 1. Effects of ionising and non-ionising radiation in cell systems and a rat model for immuno-therapy

   Author : Catrin Baureus Koch; Neurokirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kirurgi; ortopedi; traumatologi; Neurology; traumatology; transplantation; Surgery; orthopaedics; cell cultures; abscopal effect; serologi; Immunologi; serology; Immunology; rat tumour model; radiation therapy; radiation sterilisation; pulsed electric fields; interferon-gamma; immuno-gene therapy; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; glioblastoma multiforme;

   Abstract : The most malignant brain tumour, glioblastoma multiforme (GBM), has an utterly bad prognosis. In spite of all available therapy, the mean survival time is less than a year. In the unique BRIGTT project (Brain Immuno Gene Tumour Therapy), patients at the Dept of Neurosurgery. READ MORE

4. 2. Machine Learning methods in shotgun proteomics

   Author : Patrick Truong; Lukas Käll; Peter Nilsson; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry protein summarization Bayesian hierarchical modelling label-free quantification data-independent acquisition mass spectrometry; benchmark mathematical methods; transformers; computational proteomics; proteomics; bioinformatics; bert; ms2 intensity; probabilistic modelling; Biotechnology; Bioteknologi;

   Abstract : As high-throughput biology experiments generate increasing amounts of data, the field is naturally turning to data-driven methods for the analysis and extraction of novel insights. These insights into biological systems are crucial for understanding disease progression, drug targets, treatment development, and diagnostics methods, ultimately leading to improving human health and well-being, as well as, deeper insight into cellular biology. READ MORE

5. 3. Analysis of Sub-Synchronous Oscillations in Wind Power Plants

   Author : Muhammad Taha Ali; Mehrdad Ghandari; Massimo Bongiorno; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Doubly fed Induction generator; eigenvalue analysis; sub-synchronous control interaction; voltage source converter; Electrical Engineering; Elektro- och systemteknik;

   Abstract : The modern power system is moving towards the high integration of renewable energy sources at a fast pace. The integration of wind power in the power system raises many challenges along with the benefits. One of the recent challenges is the sub-synchronous oscillation (SSO) that occurs in doubly-fed induction generator (DFIG) based wind farms. READ MORE

6. 4. Modelling and Interference Analysis of AC-DC Converters for Immunity to Voltage Disturbances up to 150 kHz

   Author : Selcuk Sakar; Sarah Rönnberg; Math Bollen; Sjef Cobben; Luleå tekniska universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; AC-DC power converters; electromagnetic compatibility EMC ; high frequency disturbances; supraharmonics; switching converters; interharmonics; conducted disturbances; Electric Power Engineering; Elkraftteknik;

   Abstract : The function of electrical and electronic equipment is challenged by the high frequency emission originated from the more use of switching-based power electronic equipment and Power line communication (PLC) signaling. Investigations have shown that interferences occur in the frequency range between 2 kHz and 150 kHz, e.g. READ MORE

7. 5. Mixed Effects Modelling and Optimal Design of TNFα Response in LPS Challenge Studies - Methods and Applications in Drug Discovery

   Author : Julia Larsson; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; pharmacodynamics; pharmacokinetics; non-linear mixed effects modelling; lipopolysaccharides; tumour necrosis factor alpha; optimal design;

   Abstract : ''Endotoxin and mycoplasma are Nature’s darkest secrets. If they are ever solved, Hell itself will open.'' - Lewis Thomas* Endotoxin, or lipopolysaccharides (LPS), are heterogeneous components from the cell wall of Gram-Negative bacteria and a common challenger in the field of drug discovery. READ MORE