Search for dissertations about: "matrix metalloproteinase-12"
Found 1 swedish dissertation containing the words matrix metalloproteinase-12.
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1. Fragment Based Drug Discovery with Surface Plasmon Resonance Technology
Abstract : Fragment based drug discovery (FBDD) has been applied to two protease drug targets, MMP-12 and HIV-1 protease. The primary screening and characterization of hit fragments were performed with surface plasmon resonance -technology. Further evaluation of the interaction was done by inhibition studies and in one case with X-ray crystallography. READ MORE
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