Search for dissertations about: "matrix metalloproteinases MMPs"

Showing result 1 - 5 of 41 swedish dissertations containing the words matrix metalloproteinases MMPs.

2. 1. Matrix metalloproteinases in Helicobacter inducedgastritis

   Author : Philip Bergin; Göteborgs universitet; []
   Keywords : Helicobacter pylori; Helicobacter felis; Matrix metalloproteinase; macrophage; ; Gastritis;

   Abstract : Helicobacter pylori infects the stomach and areas of gastric metaplasia in the duodenum. Theinfection leads to peptic ulcers or gastric cancers in 10-20% of infected individuals, while themajority are more or less asymptomatic. However, active chronic gastritis develops in all infectedindividuals, often in association with atrophic gastritis. READ MORE

4. 2. Towards surgical use of matrix metalloproteinase biology

   Author : Björn Pasternak; Per Aspenberg; Pentti Tengvall; Yrjö T Konttinen; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Achilles tendon; colon; tetracyclines; tissue inhibitor of metalloproteinases TIMP ; wound healing.; colorectal surgery; extracellular matrix; humans; matrix metalloproteinases MMPs ; rats; surgical anastomosis; sutures; tendon injuries; Orthopaedics; Ortopedi;

   Abstract : Matrix metalloproteinases (MMPs), such as collagenases, are a family of enzymes capable of degrading most constituents of the extracellular matrix. MMPs are thought to be involved in the aetiopathogenesis of tendon rupture. Additionally, failure of healing has in some instances been associated with elevated levels of MMPs. READ MORE

5. 3. Effects of Asthma Combination Therapy on Extracellular Matrix Remodeling in Human Lung Fibroblasts

   Author : Lizbet Todorova; Lungbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; Proteoglycans; Lung fibroblasts; Collagen; Airway remodeling; TGFβ; Glucocorticoids; Combination therapy.; β2-agonist; MMPs;

   Abstract : Fibroblasts, being one of the resident and structural cells of the lung, have the capacity to produce inflammatory mediators, cytokines and extracellular matrix (ECM) proteins perpetuating the inflammation in the airways of asthmatics. Airway remodeling is also a prominent feature of asthma that affects the lung function causing a thickening of the airways. READ MORE

6. 4. Matrix metalloproteinases and their inhibitors in ocular neovascularization

   Author : Björn Steén; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Angiogenesis; Neovascularization; Retina; Bruch membrane; Cornea; MMP; TIMP; VEGF; In situ hybridization.;

   Abstract : Growth of pathological new vessels (angiogenesis) in the eye is a leading cause of severe vision-loss. Ocular angiogenesis is seen in the anterior part of the eye as in corneal neovascularization, or in the posterior part as in diabetic retinopathy, retinopathy of prematurity or age-related macular degeneration. READ MORE

7. 5. Matrix metalloproteinases in natural killer cells. Expression of MMPs, IL-2 activation and killer cell interactions with Matrigel® and model tumours

   Author : Per Albertsson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protease; matrix metalloproteinase; killer cell; IL-2; Matrigel; B16 melanoma; tumour infiltration; invasion assay; zymography; Western blot; RT-PCR; light microscopy; fluorescence; electron microscopy;

   Abstract : Introduction: IL-2 activated natural killer (A-NK) cells can recognize malignant cells and exert tumouricidal activities by multiple mechanisms that require close contact with the target cells. Upon adoptive transfer, some A-NK cells accumulate in tumours by migrating from the vascular bed to a position inside the malignant tissue, forming close contacts with target cells. READ MORE