Search for dissertations about: "melanocortin system"
Showing result 1 - 5 of 11 swedish dissertations containing the words melanocortin system.
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1. Cloning, Expression, Pharmacological Characterization and Anatomical Distribution of Melanocortin Receptors in an Evolutionary Perspective
Abstract : The melanocortin (MC) receptors are G-protein coupled receptors thatparticipate in several important physiological functions such as the regulation of the energy balance. This thesis focuses on the evolutionary aspect of the MC receptors and their pharmacology.One MC4 receptor and two MC5 receptor subtypes were found in a teleost fish, zebrafish. READ MORE
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2. Neurotrophic Factor Receptors in the Normal and Injured Visual System : Focus on Retinal Ganglion Cells
Abstract : The focus of this thesis is the life and death of adult retinal ganglion cells (RGCs). RGCs are neurons that convey visual information from the retina to higher centers in the brain. READ MORE
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3. Brain Stem Involvement in Immune and Aversive Challenge
Abstract : Activation of the immune system by e.g. bacteria induces the acute-phase-response and sickness behaviour. The latter encompasses among other things fever, lethargy, anorexia and hyperalgesia. READ MORE
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4. Gene Expression in the Brains of Two Lines of Chicken Divergently Selected for High and Low Body Weight
Abstract : Artificial divergent selection of chickens for high and low body weight at 8 weeks of age has produced two lines: the high (HWS) and low (LWS) body weight chicken lines. In addition to the difference in body weight, the lines show extreme differences in feeding behaviour and body composition. READ MORE
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5. The Role of the Melanocortin System in Linking Energy Homeostasis with Reward Mechanisms
Abstract : There is evidence of a link between peripheral signals of energy homeostasis and reward mechanisms. A hypothesis was formulated that the melanocortin (MC) system is part of this link. The hypothesis was tested by a series of receptor expression and neurochemical studies in rats. READ MORE