Search for dissertations about: "mesencephalon"
Showing result 1 - 5 of 28 swedish dissertations containing the word mesencephalon.
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1. Dopamine neurons in ventral mesencephalon : interactions with glia and locus coeruleus
Abstract : Parkinson’s disease is a progressive neurodegenerative disorder, characterized by a depletion of the dopaminergic neurons in the substantia nigra. The cause of the disease is yet unknown but age, oxidative stress, and neuroinflammation are some of the features involved in the degeneration. READ MORE
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2. Generation of midbrain dopaminergic neurons in vivo and in vitro: the role of Neurogenin2
Abstract : Parkinsons disease (PD) is a neurodegenerative disorder where dopaminergic neurons of the substantia nigra (SNc) in the mesencephalon are progressively eliminated. The ensuing loss of dopaminergic innervation of the basal ganglia manifests itself as severe motor deficits in PD patients. READ MORE
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3. Somatosensory projection to the mesencephalon : an anatomical study in the cat and monkey
Abstract : .... READ MORE
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4. Characterization of human dopaminergic neurons in the developing mesencephalon and upon differentiation of stem cells- for replacement therapy in Parkinson´s disease
Abstract : Cell-replacement therapy is a promising approach for treating patients with Parkinson ́s disease (PD). For this purpose, there is a need for developing a protocol that can generate high numbers of human transplantable mesencephalic dopaminer- gic (mesDA) neurons. READ MORE
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5. Identification of dopamine neuron progenitors in the embryonic midbrain and stem cell cultures - Studies on the role of neuronal subtype and differentiation state for cell replacemen in a rodent model of Parkinson's disease
Abstract : Parkinson’s Disease (PD) is a neurodegenerative disorder where the dopamine producing neurons in the ventral mesencephalon (VM) progressively die and result in symptoms such as resting tremors, muscle rigidity, slowness and difficulties in initiating movements.Currently there is no cure for PD and the available drug treatments only offer symptomatic relief and are often associated with severe side effects. READ MORE