Search for dissertations about: "metastatic bone disease"

Showing result 1 - 5 of 20 swedish dissertations containing the words metastatic bone disease.

2. 1. Metastatic bone disease

   Author : Rikard Wedin; Karolinska Institutet; Karolinska Institutet; []
   Keywords : cytology; epidemiology; metastatic bone disease; pathologic fracture; prognosis; radiotherapy; skeletal metastasis; surgical therapy; survival; MIB; p53; ER; PgR;

   Abstract : Aim: To evaluate epidemiology, prognosis and diagnostics in metastatic bone disease and identify risk factors for failure after operation for pathologic fracture. Patients: The study was based on patients treated for skeletal metastases, myeloma or lymphoma between 1986 and 1998 at the Oncology Service, Department of Orthopedics, Karolinska Hospital and on patients diagnosed with symptomatic skeletal metastases 1989-1994 in the Stockholm Region. READ MORE

4. 2. Type IV collagen in breast and colorectal cancer : a potential biomarker of metastatic disease

   Author : Moa Lindgren; Hanna Nyström; Ingrid Ljuslinder; Malin Sund; Kristian Pietras; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; colorectal liver metastases; breast cancer; breast cancer metastases; tumor marker; biomarker; stroma; type IV collagen;

   Abstract : Background: Metastatic colorectal cancer (mCRC) and metastatic breast cancer (mBC) are two leading causes of cancer-related mortality worldwide. Early detection of metastatic disease is critical, and sensitive, easily accessed and cost-effective biomarkers that can diagnose mBC and mCRC at an early stage would have high clinical value. READ MORE

5. 3. Metastatic spinal cord compression in prostate cancer : clinical and morphological studies

   Author : Sead Crnalic; Richard Löfvenberg; Anders Widmark; Anders Bergh; Sten Nilsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; bone metastasis; spinal cord compression; surgical treatment; survival prognosis; early diagnosis; androgen receptor; Orthopaedics; ortopedi; Pathology; patologi; Oncology; onkologi;

   Abstract : Background: Bone metastases occur in most patients with advanced hormone-refractory prostate cancer causing pain, pathologic fractures, and spinal cord compression. Few studies specifically address surgical treatment of metastatic spinal cord compression (MSCC) in prostate cancer. READ MORE

6. 4. Diagnosis and evaluation of therapeutic response of bone metastases

   Author : Ipek Çiray; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Bone metastases; breast neoplasm; MR imaging; CT; diagnosis; therapy evaluation; Onkologi; Oncology; Onkologi; diagnostisk radiologi; Diagnostic Radiology;

   Abstract : The aim of this study was to investigate different aspects of different imaging modalities in the diagnosis of bone metastases and in the assessment of their response to therapy. The role of CT, with and without clinical information, was investigated as compared to CT-guided bone biopsy in the evaluation of suspected bone metastases. READ MORE

7. 5. Human Bone Alkaline Phosphatase Isoforms

   Author : Per Magnusson; Markku T. Parviainen; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : Determination of serum total alkaline phosphatase (ALP) is frequently requested in clinical routine, mostly to estimate skeletal and hepatobiliary status. In this respect, clarification of the various ALP isoenzymes and isoforms contributing to the total ALP activity could be valuable in daily medical decision making. READ MORE