Search for dissertations about: "methacholine challenge"

Showing result 1 - 5 of 14 swedish dissertations containing the words methacholine challenge.

  2. 1. Optimizing and evaluation of a methacholine provocation test : with application in occupational research

    Author : Britt-Marie Sundblad; Bengt-Eric Skoogh; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; Airway responsiveness; methacholine provocation; nitric oxide; eucapnic hyperventilation; organic dust; Fysiologi; Physiology; Fysiologi; Physiology; fysiologi;

    Abstract : We have developed a methacholine provocation method, which detects bronchial responsiveness in more than 80% of healthy subjects. The method enables us to detect differences in bronchial responsiveness within the normal range. With this method FEV1 and Gaw had similar sensitivity in detecting small differences in bronchial responsiveness. READ MORE

  4. 2. The asthmatic airway response – effects on physiology and biomarkers

    Author : Henning Stenberg; allergologi och palliativ medicin Lungmedicin; []
    Keywords : Asthma; Exhaled breath temperature; Exercise; Allergen challenge; Small airways; Airway provocations; Spirometry; Impulse oscillometry; Inert gas washout; Body plethysmography; Club cell protein CC16 ;

    Abstract : Asthma is a common airway inflammatory disease, associated with a variable degree of airway obstruction. It is a heterogeneous condition with large variations in severity and clinical presentation. Moreover, disease activity can vary from time to time. Taken together, these factors make the diagnosis, monitoring and treatment of asthma challenging. READ MORE

  5. 3. Effect of allergen specific immunotherapy on allergic inflammation in the upper and lower airways

    Author : Monica Arvidsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; birch pollen allergy; cat allergy; specific immunotherapy; rush immunotherapy; experimental allergen challenge; late asthmatic response;

    Abstract : Experimental allergen challenge is widely used in diagnostic practice and research in allergy, but its relationship to environmental exposures is not clarified. Both models of allergic diseases have been used in order to examine the effects of allergen specific immunotherapy (SIT). READ MORE

  6. 4. Clinical studies of asthma phenotypes focusing on the role of the leukotrienes

    Author : Per Gyllfors; Karolinska Institutet; Karolinska Institutet; []
    Keywords : >asthma; aspirin intolerance; leukotrienes; leukotriene D4 responsiveness; methacholine responsiveness; exhaled nitric oxide;

    Abstract : Inflammation in the airways in connection to asthma is a complex phenomenon and the mechanisms underlying the associated clinical symptoms involve the interaction of many different kinds of cells and mediators, giving rise to different phenotypes. The aim of the present thesis was to investigate the molecular and cellular mechanisms that results in two of these phenotypes, i. READ MORE

  7. 5. From sneeze to wheeze: Non-invasive studies on asthma and rhinitis

    Author : David Aronsson; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway inflammation; united airways; airway hyperresponsiveness; asthma; allergíc rhinitis;

    Abstract : Asthma and allergic rhinitis are diseases that cause major disability and illness in all ethnic groups and ages. It is well established that allergic rhinitis and asthma are closely linked entities and more than 75 % of the patients with asthma reports concomitant rhinitis. READ MORE