Search for dissertations about: "mi in young"

Showing result 1 - 5 of 13 swedish dissertations containing the words mi in young.

2. 1. Cytochrome P450 pharmacogenetics : implications for anticancer and warfarin therapy

   Author : Mi-Young Lee; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : There is a pronounced interindividual variability in the drug disposition, response and toxicity. Pharmacogenetics aims at identifying genetic biomarkers that could help to increase the drug efficacy, reduce adverse drug reactions and contribute to the development of personalized medicine. READ MORE

4. 2. Preservation of male fertility in childhood acute leukemia : an experimental study addressing novel strategies and putative risks

   Author : Mi Hou; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Although treatment of cancer in young boys with cytotoxic agents has long been known to cause infertility in the survivors, the mechanisms underlying drug-induced damage to the immature testis remain unclear. A number of clinical issues associated with transplantation of testicular germ cells or tissues also require clarification. READ MORE

5. 3. Circulating immune complexes in atherosclerotic vascular disease

   Author : Awder Mustafa; Karolinska Institutet; Karolinska Institutet; []
   Keywords : circulating immune complexes; autoantibodies; lipoproteins; cardiolipin; oxidized LDL; atherosclerosis; myocardial infarction; food proteins; complement factor C4.;

   Abstract : We have investigated the association of the humoral immune factors circulating immune complexes (CICs) and autoantibodies against cardiolipin (aCL) and oxidatively modified LDL (oxLDL) to atherosclerotic vascular diseases. In a prospective nested case-control study, in which healthy 50-year-old men were followed for 20 years, the prevalence of elevated CICs and the concentration of CICs were higher in men who developed myocardial infarction. READ MORE

6. 4. Impaired glucose tolerance in ischemic heart disease

   Author : Loghman Henareh; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Diabetes mellitus; myocardial infarction; atherosclerosis; endothelial dysfunction; inflammation; microalbumiuria; left ventricular hypertrophy; tissue Doppler.;

   Abstract : Background: Diabetes mellitus (DM) and impaired glucose tolerance test (IGT) are well known risk factors for cardiovascular disease (CVD). Individuals with IGT, a prediabetic state, are asymptomatic during many years and they often remain undiagnosed until they have developed overt diabetes or cardiovascular complications. READ MORE

7. 5. Cardiovascular disease in patients with congenital heart disease

   Author : Maria Fedchenko; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Congenital heart disease; Myocardial infarction; Ischemic heart disease; Coarctation of the aorta; Cardiovascular risk factor;

   Abstract : Background: Today, about 95% of children with congenital heart disease (CHD) survive into adulthood and the survival in patients with CHD has increased considerably during the last decades. With increasing age, patients with CHD are at an increased risk of developing acquired cardiovascular disease, such as ischemic heart disease and myocardial infarction (MI). READ MORE