Search for dissertations about: "miRNA"

Showing result 1 - 5 of 152 swedish dissertations containing the word miRNA.

  2. 1. Hyperthyroidism : incidence and long term quality-of-life

    Author : Mirna Abraham Nordling; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Hyperthyroidism; Thyrotoxicosis; Graves disease; Toxic Multinodular Goitre; Solitary Toxic Adenoma; Incidence; Quality of life; Suicide;

    Abstract : Hyperthyroidism is a common disorder which in general affects approximately 2 % of women and 0.2 % of men. There are three main types of hyperthyroidism, caused by increased thyroid hormone production: Graves disease, toxic multinodular goitre and solitary toxic adenoma. READ MORE

  4. 2. Identifying and targeting vulnerabilities in cancers that metastasize to the bone and bone marrow

    Author : Adele Mirna Alchahin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Evolving technologies enable scientist to ask and seek answers to advanced questions, above and beyond. During the past decade single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of biology, in particular within cancer research. READ MORE

  5. 3. Tight-Binding Modelling of Deep Eutectic Solvent-Based Lithium Battery Electrolytes

    Author : Mirna Alhanash; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; molecular dynamics; xTB; tight-binding; deep eutectic solvent; electrolyte.;

    Abstract : In recent years, there has been a growing interest in utilizing liquid electrolytes such as deep eutectic solvents (DES) as electrolytes for lithium batteries, owing to their numerous advantageous properties, including ease of preparation, tunability, wide electrochemical stability windows, and low vapor pressures. However, an aspect that remains poorly understood is the intricate relationship between the local structural symmetry, entropy, and the macroscopic properties of DES electrolytes. READ MORE

  6. 4. miRNA and Asymmetric siRNA : Small RNAs with Large Effects on Bone Metabolism

    Author : Navya Laxman; Andreas Kindmark; Sara Windahl; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; miRNA; cp-siRNA; RNAi; bone; Osteoblast; Sequencing; Differential expression; Wnt pathway; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : RNA interference (RNAi) is a post-transcriptional gene silencing process elicited by double-stranded RNA, such as micro-RNA (miRNA) and small interfering RNA (siRNA). They are 18-25 nucleotide long, small non-coding RNAs acting as critical regulators in eukaryotic genome expression. READ MORE

  7. 5. The Role of miRNA in Neurogenesis and Cell Specification

    Author : Malin Åkerblom; Molekylär neurogenetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; miRNA; microRNA; miR-124; miR-9; miR-125; adult neurogenesis; neural stem cells; cell specification; microglia; lentiviral vectors; olfactory bulb; olfactory bulb interneurons;

    Abstract : Only a few decades ago, it was generally believed that gene expression was controlled in a unidirectional way, i.e. DNA was transcribed into RNA, which simply acted as a messenger molecule used to produce the protein that executed cellular functions. READ MORE