Search for dissertations about: "miRNAs"
Showing result 1 - 5 of 126 swedish dissertations containing the word miRNAs.
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1. MiRNAs in cancer
Abstract : There are many layers of complexity involving the processes through which somatic cells transform into malignant cancers. Historically, cancer was considered to be a disease primarily caused by gene mutations, however it is now well established that the dysregulated expression of the genes leading to the tumorigenic phenotype involves not only mutations but also epigenetic changes. READ MORE
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2. A-to-I RNA editing : Function and consequences during brain development
Abstract : The aim of my thesis has been to study how A-to-I RNA editing of miRNAs is regulated during brain development and the biological function of these editing events.Using high throughput RNA sequencing, we performed an unbiased search for edited, mature miRNAs in total mouse brain tissue from three developmental stages. READ MORE
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3. Allergic and non-allergic asthma: Translational research in immunology
Abstract : Asthma is a chronic heterogeneous respiratory disease affecting more than 300 million people globally. The different phenotypes, including allergic and nonallergic asthma, are driven by different underlying mechanisms illustrating the complexity of the disease. READ MORE
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4. Molecular studies of radiotherapy and chemotherapy in colorectal cancer
Abstract : .... READ MORE
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5. Role of Caveolae and miRNAs in Regulation of Urinary Bladder Function
Abstract : The urinary bladder is responsible for storage and expulsion of urine. Proper urination depends on an ability of the bladder to adjust to increasing volume and to contract during micturition. A disturbance of bladder contractility may affect continence. READ MORE