Search for dissertations about: "microarray immunology"
Showing result 1 - 5 of 30 swedish dissertations containing the words microarray immunology.
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1. Molecular Portraits of Cancer : Discovery of Biomarker Signatures using Affinity Proteomics
Abstract : The use of antibodies as capture molecules in assays is a common practice. By either printing monoclonal single chain fragment variables (scFvs) on a solid support – recombinant antibody microarray – or attaching them to magnetic beads – Global Proteome Survey (GPS) – we can specifically capture and measure target proteins of interest. READ MORE
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2. Protein Microarrays Based on Single Framework Recombinant Antibody Fragments (SINFABS) - Catcher and Carrier - A Crucial Combination
Abstract : Antibody-based microarrays are among the novel class of rapidly evolving proteomic technologies. In recent years, antibody microarrays have emerged as a unique tool for high-throughput protein expression profiling with great promise within biomedicine and a wide range of potential applications, including disease diagnostics and biomarker discovery. READ MORE
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3. Genomic and Molecular Aspects of Mature Human B Cells
Abstract : This thesis covers aspects of the mature human B cell and its different guises on its way to become a fully differentiated antibody forming plasma cell (AFC), the key player in the humoral immune system. The understanding of the complex molecular mechanisms taking place in the B cell, as it first encounters antigen, enters the germinal center (GC) reaction, giving rise to memory cells and plasma cells, is not only of importance for the curious scientist, but will also benefit the understanding of B cells in disease. READ MORE
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4. Dendritic cells in allergy In vitro models for studies of the human immune response
Abstract : This thesis, which is based on four original papers, deals with human dendritic cells (DCs) in immunity and allergy. DCs play a key role in the regulation of immune responses by acting as the sentinels of the immune system, specialized in the uptake of a diverse range of antigens. READ MORE
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5. Human Dendritic Cells and the Regulation of Allergic Immune Responses
Abstract : Dendritic cells (DC) are a heterogeneous lineage of bone-marrow-derived leukocytes that serve as the link between innate and adaptive immunity. They are professional antigen-presenting cells that play an important protective and regulatory role in both health and disease. READ MORE