Search for dissertations about: "micrornas"

Showing result 1 - 5 of 107 swedish dissertations containing the word micrornas.

  2. 1. MicroRNAs in Cardiometabolic Disease. With a Focus on miR-483-5p

    Author : Widet Gallo; Kardiovaskulär forskning - hypertoni; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MicroRNAs; miR-483-5p; diabetes; cardiovascular disease; BMI; Branched-chain amino acids; lifestyle; obesity;

    Abstract : .... READ MORE

  4. 2. Function and Evolution of Small Regulatory RNAs and their Associated Proteins : A Journey from Genome to Proteome

    Author : Bart Edelbroek; Fredrik Söderbom; Jonathan R. Chubb; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; microRNAs; non-coding RNAs; Evolution; Whole Genome Sequencing; Transcriptomics; Proteomics; small RNAseq; Amoebozoa; Multicellular development; Social amoebae; Comparative genomics; Genome annotation; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Organisms throughout the tree of life have evolved distinct ways to regulate gene expression. Some of these processes involve non-coding RNAs (ncRNAs), which are not translated but functional nonetheless. These ncRNAs are of utmost importance, with dysregulation of some causing severe developmental effects or even being lethal. READ MORE

  5. 3. Heart Regeneration : Lessons from the Red Spotted Newt

    Author : Nevin Witman; Jamie Morrison; Thomas Braun; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Heart; Regeneration; Newt; microRNAs; RNA editing; Molecular Biology; molekylärbiologi;

    Abstract : Unlike mammals, adult salamanders possess an intrinsic ability to regenerate complex organs and tissue types, making them an exciting and useful model to study tissue regeneration. The aims of this thesis are two fold, (1) to develop and characterize a reproducible cardiac regeneration model system in the newt, and (2) to decipher the cellular and molecular underpinnings involved in regeneration. READ MORE

  6. 4. Chemokine-Mediated Migration of Colon Cancer Cells

    Author : Amr Al-Haidari; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colon cancer cells; Colon cancer metastasis; Cancer cell migration; Chemokines; Rho GTPases; MicroRNAs;

    Abstract : .... READ MORE

  7. 5. Identification of miRNA expression profiles for diagnosis and prognosis of prostate cancer

    Author : Jessica Carlsson; Karin Klinga Levan; Björn Olsson; Gisela Helenius; Pernilla Wikström; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; microRNAs; prostate zones; normalization; endogenous controls; Medicin; Medicine;

    Abstract : Cancer of the prostate (CaP) is the most common malignancy diagnosed in men in the Western society. During the last years, prostate specific antigen (PSA) has been used as a biomarker for CaP, although a high PSA value is not specific for CaP. Thus, there is an urgent need for new and improved diagnostic markers for CaP. READ MORE