Search for dissertations about: "microvascular pathology"

Showing result 1 - 5 of 12 swedish dissertations containing the words microvascular pathology.

  2. 1. The matter of white matter in Alzheimer's disease. -On white matter disease from neuropathology and neuroimaging to clinical presentation

    Author : Martin Sjöbeck; Lund Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; medicinsk instrumentering; tomografi; radiologi; Klinisk fysiologi; medical instrumentation; tomography; radiology; executive dysfunction; Clinical physics; magnetic resonance imaging; diffusion tensor imaging; neuropathology; microvascular pathology; astrocytes; myelin; oligodendrocytes; white matter disease; Alzheimer s disease; neuropsychology; neuropsykologi; Neurologi; neurophysiology; neurofysiologi; Psychiatry; clinical psychology; psychosomatics; Psykiatri; klinisk psykologi; psykosomatik; Neurology;

    Abstract : Alzheimer's disease (AD) is the most prevalent type of dementing disorder. The cortical pathology of AD has been recognized for almost a century. In later years, an associated pathological feature of AD has been identified which affects the white matter. READ MORE

  4. 2. Observations on cerebral amyloid angiopathy and microvascular pathology in Alzheimer's disease and vascular dementia

    Author : Mattias Haglund; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Patologi allmän ; pathological anatomy; General pathology; Vascular dementia; Alzheimer s disease; Cerebral infarction; Locus ceruleus; White matter; Microvasculature; Cerebrovascular disease; patologisk anatomi; Ischemia; Cerebral amyloid angiopathy;

    Abstract : Dementia is a state of permanent loss of cognitive function, most commonly affecting the elderly. With a rapidly growing aged population, the spectrum of disorders that lead to dementia is exerting an ever-increasing toll on patients, families and society alike. The most common dementing disorders are Alzheimer's disease and vascular dementia. READ MORE

  5. 3. Molecular Mechanisms in Endothelial Cell Differentiation

    Author : Emma Rennel; Pär Gerwins; Lena Claesson-Welsh; Ian Zachary; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; angiogenesis; FGF-2; VEGF-A; signal transduction; in vitro angiogenesis assay; immortalized brain endothelial cells; H-Ras; tetracycline-regulated gene expression; microarray; telomerase immortalized human microvascular endothelial cells; differentiation; Patologi; Pathology; Patologi;

    Abstract : Angiogenesis is the formation of new blood vessels from the pre-existing blood vessels. Blood vessels are composed of endothelial cells and supporting musculature. Angiogenesis is regulated by numerous soluble ligands and by cell-matrix interactions. READ MORE

  6. 4. Inflammatory mechanisms in experimental CNS trauma

    Author : Jonas Isaksson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Spinal cord injury; brain injury; ICAM-1; P-selectin; iNOS; inflammation; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Traumatic brain and spinal cord injuries are important causes of premature death and permanentdisability. To improve the treatment of CNS-injured patients increased knowledge about thepathophysiological events that mediate death or dysfunction of nervous tissue is urgently needed. READ MORE

  7. 5. Microvascular disease in cognitive impairment

    Author : Mana Shams; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Cerebral small vessel disease has been recognized as the greatest vascular contributor to dementia. Previously, small vessel disease was thought to be part of normal aging. READ MORE