Search for dissertations about: "mitochondrial complex II"

Showing result 1 - 5 of 91 swedish dissertations containing the words mitochondrial complex II.

2. 1. Mitochondrial medicine. New strategies to evaluate drug toxicity and develop pharmacological protection of the cell’s powerhouse

   Author : Sarah Piel; Klinisk neurofysiologi; []
   Keywords : mitochondria; drug-induced mitochondrial toxicity; mitochondrial disease; mitochondrial medicine; drug development; succinate; methylene blue; metformin; acetaminophen; paracetamol; Kolliphor® EL;

   Abstract : Mitochondria produce the majority of the cell’s energy. Any dysfunction in, or interference with mitochondrial function can have severe consequences. And yet, it was only within the last decades that screening for potential mitochondrial toxicity was included as routine toxicity assay during early drug development. READ MORE

4. 2. Biogenesis of the bc1 complex in mitochondria

   Author : Katharina Stephan; Martin Ott; Daniel Daley; Erika Fernandez-Vizarra; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Respiratory chain; bc1 complex assembly; mitochondrial protein biogenesis; molecular biology; yeast; Biochemistry; biokemi;

   Abstract : Mitochondria perform a variety of tasks, but the function they are most prominent for is the energy conversion to form ATP, the universal energy equivalent of the cell. The majority of this ATP is created by the oxidative phosphorylation system, consisting of the respiratory chain and the ATP synthase. READ MORE

5. 3. Signalling in plant mitochondria. Redox regulation of gene expression & characterisation of a pea nucleoside diphosphate kinase

   Author : Martha L Escobar Galvis; Biokemi och Strukturbiologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; mitochondrial gene expression; redox; respiratory complex II; NDPK; protein interactions; heat-stress; Växtbiokemi; Plant biochemistry;

   Abstract : This work contributes to our understanding of mitochondrial responses to changing environmental conditions in plants. The first part of this thesis is focused in the study of redox regulation of mitochondrial gene expression. By using inhibitors, the redox state of the components of the mitochondrial respiratory chain was selectively affected. READ MORE

6. 4. Systems biology of mitochondrial dysfunction

   Author : Florian A Schober; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The human body consumes vast amounts of metabolites that are transformed into one another, modified to useful building blocks and broken down to harvest their energy. Mitochondria are at the core of this metabolic turnover and oxidative phosphorylation provides most cellular ATP in almost all human tissues. READ MORE

7. 5. Gene description, activity quantification and physiological responses of mitochondrial alternative NAD(P)H dehydrogenases

   Author : Fredrik Johansson; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; phytogeography; chemotaxonomy. Physiology of nonvascular plants; Systematisk botanik; taxonomi; morfologi; kemotaxonomi. Växters fysiologi inte kärlväxter .; morphology; taxonomy; Systematic botany; plant mitochondria; NAD P H dehydrogenases; cold treatment; complex I; light dependence; antimycin a; alamethicin;

   Abstract : In addition to proton-pumping complex I, the plant respiratory chain contains type II NAD(P)H dehydrogenases. These extra enzymes do not pump protons and consequently do not contribute to the electrochemical proton gradient. READ MORE