Search for dissertations about: "molecular chaperone"
Showing result 1 - 5 of 118 swedish dissertations containing the words molecular chaperone.
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1. The molecular chaperone CCT: Functions beyond folding
Abstract : The chaperonin-containing tailless complex polypeptide 1 (CCT) is a eukaryotic ~1 MDa barrel shaped molecular chaperone, built up by eight distinct subunits and is required for the folding of the abundant cytoskeletal proteins actin and tubulin. CCT exists as an assembled oligomer, micro-complexes and as individual subunits in the cell. READ MORE
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2. Type III secretion- the various functions of the translocon operon in bacterial pathogenesis
Abstract : In order to establish colonisation of a human host, pathogenic Yersinia use a type III protein secretion system to directly intoxicate host immune cells. Activation of this system requires target cell contact and is a highly regulated process. READ MORE
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3. Human copper ion transfer : from metal chaperone to target transporter domain
Abstract : Many processes in living systems occur through transient interactions among proteins. Those interactions are often weak and are driven by small changes in free energy. READ MORE
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4. Multiple twists in the molecular tales of YopD and LcrH in type III secretion by Yersinia pseudotuberculosis
Abstract : The type III secretion system (T3SS) is a highly conserved secretion system among Gram negative bacteria that translocates anti-host proteins directly into the infected cells to overcome the host immune system and establish a bacterial infection. Yersinia pseudotuberculosis is one of three pathogenic Yersinia spp. READ MORE
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5. Molecular Aspects of Transthyretin Amyloid Disease
Abstract : This thesis was made to get a deeper understanding of how chaperones interact with unstable, aggregation prone, misfolded proteins involved in human disease. Over the last two decades, there has been much focus on misfolding diseases within the fields of biochemistry and molecular biotechnology research. READ MORE