Search for dissertations about: "molekylär immunologi"

Showing result 1 - 5 of 78 swedish dissertations containing the words molekylär immunologi.

  2. 1. Malaria during pregnancy and childhood : A focus on soluble mediators and neutrophils

    Author : Stéphanie Boström; Marita Troye-Blomberg; Maria Yazdanbakhsh; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plasmodium falciparum; pregnancy; childhood; neutrophils; biomarkers; cytokines; chemokines; antibodies; Fulani; Dogon; immunologi; Immunology;

    Abstract : In areas where malaria is endemic, pregnant women and children bear the main burden of severe and life-threatening malarial disease. The aim of this work was to study the impact of Plasmodium falciparum infection on inflammatory responses in pregnant women and children residing in African countries. READ MORE

  4. 2. Role of alveolar epithelial cells in macrophage responses against mycobacterial infections

    Author : Olga Daniela Chuquimia Flores; Carmen Fernández; Diana Boraschi; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Lung; alveolar epithelial cells; macrophages; AEC-derived media; control of intracellular bacterial growth; mycobacterial infections; immunologi; Immunology;

    Abstract : This thesis aimed to investigate the role of alveolar epithelial cells (AEC) on immune responses against mycobacterial infections, specifically, the role of AEC in modulating macrophage functions through the secretion of broad variety of factors.In paper I, we compared murine AEC with interstitial macrophages (PuM) in their ability to take up and control mycobacterial growth and their capacity as antigen-presenting cells. READ MORE

  5. 3. Activation, adhesion and motility of B lymphocytes in health and disease

    Author : Natalija Gerasimcik; Eva Severinson; Victor Tybulewicz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; B cells; activation; motility; IL-4; EBV; Dock10; Cdc42; Rac1 and Rac2; immunologi; Immunology;

    Abstract : B cells can be activated by T cell-dependent stimuli, such as CD40 ligation and cytokines, which induce extensive proliferation, class switch recombination and somatic hypermutation.Epstein-Barr virus (EBV) can also induce B cell activation by mimicking T cell help through its main oncoprotein, latent membrane protein 1 (LMP-1). READ MORE

  6. 4. Lactobacilli- and Staphylococcus aureus mediated modulation of immune responses in vitro

    Author : Yeneneh Haileselassie; Eva Sverremark-Ekström; Huub Savelkoul; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; lactobacilli; staphylococcus aureus; dendritic cells; retinoic acid; epithelial cells; T cells; immunologi; Immunology;

    Abstract : The human gut harbors a vast number of microbes. These microbes are not passive bystanders. They are important in modulating the immune system. We have previously shown that early colonization with lactobacilli and Staphylococcus (S. READ MORE

  7. 5. Infant gut microbiota, immune responses and allergic disease during childhood

    Author : Maria A. Johansson; Eva Sverremark-Ekström; Christina West; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

    Abstract : The early-life microbiota is important for postnatal immune maturation and implied in immune mediated diseases. The aim of this work was to study specific species of bacteria in the gut microbiota and relate them to immune function and allergic disease during childhood. READ MORE