Search for dissertations about: "multiple medication"

Showing result 1 - 5 of 52 swedish dissertations containing the words multiple medication.

2. 1. Safety of Medication in Paediatrics

   Author : Kristina Star; Karin Nordin; I Ralph Edwards; Richard Irvin Cook; Uppsala universitet; []
   Keywords : paediatrics; adverse drug reaction; drug-related problem; medication error; patient safety; individual case safety reports; pharmacovigilance; medication; nurses; health care personnel; dosage form; NSAID; dosing; prescription; antipsychotic medicines; postmarketing surveillance; Medicinsk vetenskap; Medical Science;

   Abstract : Background: In paediatrics, the limited documentation to guide medication, the lack of suitable dosage forms, and the continuous development in childhood present a scenario where safety of medication is a particular challenge.Aim: To explore reported adverse drug reactions (ADRs) and the challenges in prescribing and administering medicines in paediatrics, in order to identify and suggest areas needing international surveillance within medication safety and improvement in the clinical setting. READ MORE

4. 2. On drug use, multiple medication and polypharmacy in a national population

   Author : Bo Hovstadius; Göran Petersson; Sven Tågerud; Bengt Åstrand; Björn Wettermark; Linnéuniversitetet; []
   Keywords : drug use; multiple medication; polypharmacy; register; prevalence; therapeutic intensity; acquisition cost.; NATURAL SCIENCES; NATURVETENSKAP; Biomedical Sciences; Biomedicinsk vetenskap;

   Abstract : The application of multiple medications has successively increased during a number of years and has thereby increased the potential risks of adverse drug reactions, interactions and non-adherence to drug therapy. This may result in unnecessary health expenditure, directly due to redundant drug sales, and indirectly due to the increased hospitalization caused by drug-related problems. READ MORE

5. 3. Medication reviews by clinical pharmacists in older hospitalised patients : Implementation, performance and effects

   Author : Thomas G. H. Kempen; Ulrika Gillespie; Håkan Melhus; Elisabet I. Nielsen; Derek Stewart; Stephen Byrne; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medication review; medication reconciliation; multi-professional collaboration; hospital medicine; polypharmacy; inappropriate prescribing; drug-related problems; medication-related hospital admissions; pragmatic clinical trial; cluster analysis; randomised controlled trial; qualitative analysis; process evaluation; implementation science; Geriatrics; Geriatrik; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy; Internal Medicine; Internmedicin; Hälso- och sjukvårdsforskning; Health Care Research;

   Abstract : Background Inappropriate use of medications is a leading cause of avoidable harm in health care. Medication reviews by clinical pharmacists improve medication use, but evidence on hard clinical outcomes in older hospitalised patients is scarce and implementation in practice is challenging. READ MORE

6. 4. Acquired epilepsy in Multiple sclerosis: a nationwide register-based investigation into prognosis and treatment

   Author : Zamzam Mahamud; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple sclerosis; epilepsy; seizure; diagnosis; mortality; antiseizure medication; prevalence; incidence;

   Abstract : The prevalence of epilepsy in persons with multiple sclerosis (MS) is thrice that of the general population. The association between epilepsy and MS prognosis and its management are however largely unknown. The prevalence of concomitant MS and epilepsy is low, making recruitment of sufficient numbers of patients for single-centre studies difficult. READ MORE

7. 5. Longitudinal Models for Quantifying Disease and Therapeutic Response in Multiple Sclerosis

   Author : Ana M. Novakovic; Mats O. Karlsson; Etienne Pigeolet; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nonlinear mixed-effects models; pharmacometrics; NONMEM; multiple sclerosis; cladribine; EDSS; item response theory; relapse rate; absolute lymphocyte count; total volume T2 lesions; burden of disease; power; sample size; Pharmaceutical Science; Farmaceutisk vetenskap;

   Abstract : Treatment of patients with multiple sclerosis (MS) and development of new therapies have been challenging due to the disease complexity and slow progression, and the limited sensitivity of available clinical outcomes. Modeling and simulation has become an increasingly important component in drug development and in post-marketing optimization of use of medication. READ MORE