Search for dissertations about: "myocardial angiogenesis"

Showing result 1 - 5 of 16 swedish dissertations containing the words myocardial angiogenesis.

  2. 1. Molecular Regulation of Angiogenesis

    Author : Sofie Mellberg; Lena Claesson-Welsh; Frank Böhmer; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endothelial morphogenesis; VEGFR-2; protein tyrosine phosphatase; VE-PTP; PTPRB; endocan; ESM-1; angiogenesis; Molecular medicine; Molekylär medicin;

    Abstract : Angiogenesis, de novo formation of blood vessels from the pre-existing vasculature, is crucial in embryo development, and in processes in the adult such as wound healing and ovulation. Angiogenesis is also involved in pathological conditions such as cancer and chronic inflammatory diseases, which are propagated by dysregulated, excess angiogenesis. READ MORE

  4. 2. Therapeutic myocardial angiogenesis and its pharmacological modulation

    Author : Anwar J Siddiqui; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Angiogenesis; arteriogenesis; ischemic heart; vascular endothelial growth factor; angiopoietin and receptor;

    Abstract : Angiogenesis is the formation of new blood vessels induced by the proliferation and migration of endothelial cells. Because angiogenesis is a complex process, therapeutic efficacy may be improved by overexpression of combined angiogenic factors. READ MORE

  5. 3. Interleukin-6 Signaling Pathways in Human Vascular Endothelial Cells : Molecular Mechanisms and Associations to Atherosclerosis

    Author : Mulugeta Melkie Zegeye; Liza Ljungberg; Allan Sirsjö; Ashok K Kumawat; Magnus Grenegård; Stefan Rose-John; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HUVECs; Angiogenesis; Laminins; Transmigration; Biomarker; Cytokine; Inflammation; Myocardial infarction;

    Abstract : Interleukin-6 is pleotropic cytokine produced by several types of cells including endothelial cells (ECs). IL-6 acts on target cells via two major signaling mechanisms known as classic signaling and trans-signaling. READ MORE

  6. 4. Myocardial Topical Negative Pressure

    Author : Sandra Lindstedt Ingemansson; Thoraxkirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary blood flow; microvascular blood flow; topical negative pressure TNP ;

    Abstract : The aim of this research was to find out if it is possible to increase myocardial microvasular blood flow by applying a topical negative pressure source directly onto the myocardium. Topical negative pressure is a relatively new wound healing technique. READ MORE

  7. 5. Myocardial angiogenesis : aspects on endogenous determinants and effects of stimulation

    Author : Agneta Månsson Broberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Myocardial infarction; ischemia; angiogenesis; VEGF- A165; gene therapy; adenovirus; plasmid; ephrinB2; darbepoietin-alpha; apoptosis; estrogen receptors;

    Abstract : Background: Therapeutic angiogenesis using i.e. VEGF and FGF have shown beneficial effects, however, delivery routes and other modulating agents have not been thoroughly investigated. In this study the efficacy of adenovirus gene transfer was compared to plasmid gene transfer. READ MORE