Search for dissertations about: "myocardial hypertrophy"

Showing result 1 - 5 of 37 swedish dissertations containing the words myocardial hypertrophy.

  2. 1. Cardiac hypertrophy : transcription patterns, hypertrophic progression and extracellular signalling

    Author : Nina Gennebäck; Stellan Mörner; Anders Waldenström; Urban Hellman; Ali J Marian; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac hypertrophy; HCM; gene expression; OPLS-DA; multivariate dataanalysis; cardiomyocytes; exosomes; microvesicles; Medicine; medicin;

    Abstract : Background: The aim of this thesis was to study transcription patterns and extracellular signalling of the hypertrophic heart to better understand the mechanisms initiating, controlling and maintaining cardiac hypertrophy.Cardiac hypertrophy is a risk factor for cardiovascular morbidity and mortality. READ MORE

  4. 2. Myocardial metabolism in experimental infarction and heart failure

    Author : Truls Råmunddal; Göteborgs universitet; []
    Keywords : Myocardial metabolism; Heart failure; Myocardial infarction; Lipotoxic heart disease; Apolipoprotein B; Arrhythmias; Cardiac reserve; Creatine metabolism;

    Abstract : Abstract The heart is an organ heavily dependent on exogenous lipids for the oxidative production of adenosine-triphosphate (ATP) and therefore maintenance of normal cellular energy homeostasis. However, high energy flux organs such as the heart must closely match lipid import and utilization or otherwise lipids will accumulate in the cardiomyocytes. READ MORE

  5. 3. Assessment of myocardial viability using magnetic resonance imaging

    Author : Robert Jablonowski; Lund Klinisk fysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic resonance imaging; myocardial infarction; hypertrophic cardiomyopathy; fibrosis; viability;

    Abstract : Myocardial infarction (MI) following an acute coronary occlusion is a leading cause of morbidity and mortality. During revascularization, microemboli may complicate treatment and affect cardiac function. The long-term effects of microembolization are not fully elucidated. READ MORE

  6. 4. Myocardial creatine metabolism in experimental infarction and heart failure

    Author : Malin Lindbom; Göteborgs universitet; []
    Keywords : Energy metabolism; Creatine; Congestive heart failure; Myocardial infarction; Ventricular arrhythmias; Cardiac remodeling; apolipoprotein B; Lipid metabolism;

    Abstract : The failing heart is characterized by changes in structure, function and metabolism. All these changes are usually defined as pathologic remodelling. An important part of this negative remodelling process is disturbances in the myocardial energy metabolism. READ MORE

  7. 5. Early parathyroidectomy in mild primary hyperparathyroidism: Effects on heart and bones

    Author : Erik Almqvist; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; parathyroidectomy; hyperparathyroidism; bone metabolism; testosterone; myocardial hypertrophy; cardiac function; echocardiography; radionuclide angiography; natriuretic peptide; Surgery; orthopaedics; traumatologi; ortopedi; traumatology; Kirurgi;

    Abstract : There is an ongoing controversy regarding how to take care of patients with mild primary hyperparathyroidism (PHPT). Some recommend surgical treatment at diagnosis, others just follow-up as long as there is no evidence of disease progression. READ MORE