Search for dissertations about: "nanoelectrospray ionization"
Found 5 swedish dissertations containing the words nanoelectrospray ionization.
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1. New methods for sensitive analysis with nanoelectrospray ionization mass spectrometry
Abstract : In this thesis, new methods that address some current limitations in nanoelectrospray mass spectrometry (nESI-MS) analysis are presented. One of the major objectives is the potential gain in sensitivity that can be obtained when employing the proposed techniques. READ MORE
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2. Mass Spectrometry with Electrospray Ionization from an Adjustable Gap
Abstract : In this thesis the fabrication and analytical evaluation of two new electrospray emitters utilized for mass spectrometry analysis is presented. The emitters are based on a new concept, where the spray orifice can be varied in size. The thesis is based on two papers. All present-day nanoelectrospray emitters have fixed dimensions. READ MORE
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3. Sample preconcentration in open microchannels : Combinations with MALDI and nano-ESI mass spectrometry and computer simulations
Abstract : In this thesis a novel concept for preconcentration of biomolecules in open microchannels is presented. The preconcentration is based on electromigration of charged analytes, and detection is performed with matrix-assisted laser desorption/ionization (MALDI) or nano-electrospray ionization (nESI) mass spectrometry (MS). READ MORE
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4. Miniaturized Techniques for Protein Analysis
Abstract : Proteins are a highly diversified group of molecules, andfor their study, advanced analytical tools are required. Inparticular, a need for high-throughput techniques has emergedin order to enable the characterization of large sets ofproteins. READ MORE
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5. Electrospray Ionization Mass Spectrometry for Determination of Noncovalent Interactions in Drug Discovery
Abstract : Noncovalent interactions are involved in many biological processes in which biomolecules bind specifically and reversibly to a partner. Often, proteins do not have a biological activity without the presence of a partner, a ligand. READ MORE