Search for dissertations about: "narcolepsy"

Showing result 1 - 5 of 9 swedish dissertations containing the word narcolepsy.

  2. 1. Narcolepsy in children: Relationship to the H1N1 influenza vaccination, association with psychiatric and cognitive impairments and consequences in daily life

    Author : Attila Szakacs; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; narcolepsy; incidence; children; psychiatric comorbidity; cognition; adaptive behavior; quality of life; parenting stress;

    Abstract : Background/aims: Narcolepsy is a lifelong sleep disorder with an onset most frequently in the second decade of life. The cardinal symptoms are excessive daytime sleepiness, cataplexy, hypnagogic and hypnopompic hallucinations sleep paralysis and disturbed nighttime sleep. READ MORE

  4. 2. Brain Networks and Dynamics in Narcolepsy

    Author : Natasha Morales Drissi; Maria Engström; Gunnar Cedersund; Fredrik Elinder; Birgitte Kornum; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Narcolepsy is a chronic sleep disorder, characterised by excessive daytime sleepiness with frequent uncontrollable sleep attacks. In addition to sleeprelated problems, changes in cognition have also been observed in patients with narcolepsy and has been linked to the loss of Orexin-A in a number of studies. READ MORE

  5. 3. Autoimmunogenetic Aspects of Vaccine-induced Narcolepsy. As part of the AMINA - Autoimmune Multiple Sclerosis and Narcolepsy Study

    Author : Alexander Lind; Pediatrisk endokrinologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Narcolepsy type 1 (NT1) is a neurological sleep disorder. The biological cause is the degeneration of hypocretin neurons located in the hypothalamus. It has been suggested that NT1 has an autoimmune pathogenesis, as in most patients, the Human Leukocyte Antigen (HLA)-DQB1*06:02:01 is present. READ MORE

  6. 4. Human leukocyte antigens with special reference to association and linkage in multiple sclerosis

    Author : Anna Fogdell-Hahn; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HLA; MHC; multiple sclerosis; narcolepsy; lod score; linkage.;

    Abstract : The polymorphism of HLA (human leukocyte antigen) is extensive. Allelic variation has previously been detected by cellular and serological methods. Today a variety of genomic typing techniques have been developed, which give higher resolution and a possibility to detect single nucleotide variations. READ MORE

  7. 5. Vaccine safety, vaccine effectiveness and other determinants for successful immunisation programmes

    Author : Favelle Lamb; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The studies in this thesis examined several key determinants for successful uptake of vaccinations in the Nordic countries, with focus on vaccine safety and vaccine effectiveness. In study I, we investigated whether disease history is a risk factor for narcolepsy after vaccination with the pandemic influenza vaccine, Pandemrix, which was circulated between 2009 and 2010. READ MORE