Search for dissertations about: "nerve degeneration"

Showing result 1 - 5 of 57 swedish dissertations containing the words nerve degeneration.

2. 1. The Chorda Tympani Nerve : Role in Taste Impairment in Middle Ear Disease and after Ear Surgery

   Author : Katarina Berling Holm; Magnus von Unge; Mikael Karlberg; Uppsala universitet; []
   Keywords : Chorda tympani nerve; ear surgery; taste; chronic suppurative otitis media; otosclerosis; electrogustometry; filter paper disc method; quality of life; transmission electron microscopy; degeneration; sprouting; Surgery; Kirurgi;

   Abstract : The chorda tympani nerve, also known as the taste nerve, runs uncovered through the middle ear cavity, a localization that exposes the nerve to pathological processes and surgical trauma in the middle ear. People operated on for otosclerosis tend to complain more about postoperative taste disturbances than those operated on for chronic otitis media. READ MORE

4. 2. An exploration of the mechanisms behind peripheral nerve injury

   Author : Rebecca Wiberg; Liudmila Novikova; Paul Kingham; Ash Mosahebi; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peripheral nerve injury; target organ; spinal motoneurons; primary sensory neurons; degeneration; anatomi; Human Anatomy;

   Abstract : Despite surgical innovation, the sensory and motor outcome after peripheral nerve injury is incomplete. In this thesis, the biological pathways potentially responsible for the poor functional recoveries were investigated in both the distal nerve stump/target organ, spinal motoneurons and dorsal root ganglia (DRG). READ MORE

5. 3. Magnetic resonance imaging, electroneurographic, and clinical findings in Bell's palsy

   Author : Mats Engström; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Bell s palsy; facial nerve; magnetic resonance imaging; gadolinium; electroneurography; clinical grading; neurapraxia; nerve degeneration; prognostication; Kirurgi; Surgery; Kirurgi; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

   Abstract : Seventy-two patients were examined in order to learn more about the pathophysiology of Bell's palsy and to assess the value of magnetic resonance imaging (MRI) as well as electroneurographic and clinical tests in predicting the outcome in patients with this disease.In 12 of 20 patients (60%) an increased signal intensity in the paranasal sinuses was evident on T2-weighted MRI scans in the early stage of palsy, and in six of the positive patients the high signal intensity had disappeared by the time of the follow-up examination. READ MORE

6. 4. Clusterin and Megalin in The Spinal Cord

   Author : Grzegorz Wicher; Hakan Aldskogius; Lars Hillered; Anders Lewen; Robin Franklin; Uppsala universitet; []
   Keywords : Neurosciences; nerve degeneration; hypoglossal nerve; chaperone; apolipoprotein; development; transcription factor; astrocyte; glial differentiation; myelin; cell signalling; Neurovetenskap;

   Abstract : Nerve injury induces up-regulation of the chaperone protein clusterin in affected neurons and adjacent astrocytes but the functional significance of this response is unclear. We find that motor neuron survival is significantly greater in clusterin(+/+) compared to (-/-) mice. READ MORE

7. 5. On dopamine neurons : nerve fiber outgrowth and L-DOPA effects

   Author : Sara af Bjerkén; Ingrid Strömberg; Kathy Steece-Collier; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; nerve fiber outgrowth; astrocytes; ventral mesencephalon; GDNF; L-DOPA; L-DOPA induced dyskinesia; Neurobiology; Neurobiologi;

   Abstract : Parkinson’s disease is a disorder mainly characterized by progressive degeneration of dopamine producing neurons in the substantia nigra of the midbrain. The most commonly used treatment strategy is to pharmacologically restore the lost function by the administration of the dopaminergic precursor L-DOPA. READ MORE