Search for dissertations about: "neurite"
Showing result 1 - 5 of 89 swedish dissertations containing the word neurite.
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1. The role of PKC in neuronal differentiation and in regulation of the actin cytoskeleton during neurite outgrowth
Abstract : Protein kinase C (PKC) is a family of serine/threonine kinases subgrouped into classical (α, βI, βII, γ), novel (δ, ε, η, θ) and atypical (ζ, ι/λ) isoforms. PKC can be activated by phorbol esters, and prolonged treatment of neuroblastoma cells has been shown to induce neuronal differentiation with neurite outgrowth and increased expression of neuronal genes. READ MORE
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2. Ras-MAPK signaling in differentiating SH-SY5Y human neuroblastoma cells
Abstract : Neuroblastoma is a malignant childhood cancer, originating from sympathetic neuroblasts of the peripheral nervous system. Neuroblastoma is a heterogenous group of tumours, while some are highly malignant others can spontaneosly mature into a more benign form or regress. READ MORE
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3. Studies on Peripheral Nerve Regeneration: Microdispensing, Neurite Guidance and Galectins
Abstract : The present thesis describes development of a microdispenser-based technique to create of protein patterns for neurite guidance. The same technique was also developed to allow direct positioning of dissociated cells, including neurons, on cell culture substrates. Finally the role of galectin-3 and 8 during nerve regeneration was investigated. READ MORE
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4. Localisation of Protein Kinase C in Apoptosis and Neurite Outgrowth
Abstract : Protein kinase C (PKC) is a family of serine/threonine kinases, which are subgrouped into classical (a, bI, bII, g), novel (d, e, h, q) and atypical (z, i/l) isoforms. One major aim of this thesis work was to investigate if altered levels of PKC isoforms influence the apoptotic responses of malignant cell-lines. READ MORE
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5. Composite Regenerative Scaffolds
Abstract : Regenerative medicine and tissue engineering solutions of heavily innervated tissues are at this point lacklustre. This thesis expands our knowledge of appropriate acellular scaffolds for tissue repair in general and nerve regeneration in particular. READ MORE