Search for dissertations about: "neuroblastoma"

Showing result 1 - 5 of 172 swedish dissertations containing the word neuroblastoma.

  1. 1. Gene therapy of neuroblastoma

    University dissertation from Göteborg

    Author : Yvonne Arvidsson; Göteborgs universitet.; Gothenburg University.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroblastoma; gene therapy; PNP; ASK1; MASH1; IL-12; GM-CSF; immunotherapy; apoptosis.;

    Abstract : Aims: The survival of children with advanced stages of neuroblastoma has not improved significantly during recent years. Therefore additional treatments based on other modalities need to be developed. The objective of this thesis was to investigate the possibility to develop gene therapy of neuroblastoma. READ MORE

  2. 2. Angiostatic treatment of neuroblastoma

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erik Wassberg; Uppsala universitet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Angiogensis; Angiostatic treatment; Apoptosis; Chromogranin A; Differentiation; Neuroblastoma; 2-Methoxyestradiol; 2-Propynylestradiol; TNP-470; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; Medical Cell Biology; medicinsk cellbiologi;

    Abstract : Neuroblastoma is a malignant solid tumor of childhood with a poor prognosis. The growth of solid tumors has been shown to be dependent on new blood vessel formation, i.e. angiogenesis. READ MORE

  3. 3. Polyamine analogues inhibit neuroblastoma cell growth

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erika Söderstjerna; Lunds universitet.; Lund University.; [2011]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; survivin; cell cycle; polyamine analogue; polyamines; apoptosis; neuroblastoma; MYCN;

    Abstract : Popular Abstract in Swedish Summary in Swedish Populärvetenskaplig sammanfattning Neuroblastom uppstår ur omogna nervceller i binjurarna eller i nervvävnaden bredvid ryggraden och är den vanligaste extrakraniala solida tumörformen hos barn. Varje år drabbas ca 10-15 barn i Sverige och sjukdomen uppkommer vanligast hos barn under 4 år. READ MORE

  4. 4. Genetic alterations in Scandinavian neuroblastoma tumors

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Katarina Ejeskär; Göteborgs universitet.; Gothenburg University.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; loss of heterozygozity; deletion; 1p; 3p; CDC2L1; TP73; CORT; FHIT;

    Abstract : The results presented here derive from our efforts to find genes and chromosomal regions of interest in the formation and progression of the childhood tumor neuroblastoma.Neuroblastoma is the most common extracranial solid tumor of childhood. READ MORE

  5. 5. Notch Signaling in Human Neuroblastoma Cells

    University dissertation from Department of Laboratory Medicine, Lund University

    Author : Marie Stockhausen; Lunds universitet.; Lund University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Hes-1; Medicin människa och djur ; Medicine human and vertebrates ; hypoxia; TGF-alpha; EGFR; ERK1 2; Ras MAPK; differentiation; valproic acid; ubiquilin-1; neuroblastoma; Hash-1; Cytologi; onkologi; cancer; cancerology; Cytology; Notch;

    Abstract : Neuroblastoma is a childhood tumor derived from the sympathetic nervous system (SNS). It is believed that the tumors arise from cells halted in their differentiation and due to their immature phenotype; they express proteins normally only detected during embryogenesis. One such protein is Hash-1, which is required for formation of the SNS. READ MORE