Search for dissertations about: "neuroblastoma"
Showing result 21 - 25 of 226 swedish dissertations containing the word neuroblastoma.
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21. Hypoxia-induced phenotypic modulation of human neuroblastoma cells
Abstract : Neuroblastoma is a childhood tumour derived from cells of the sympathetic nervous system, which are arrested at low differentiation stages. Low differentiation stage and high tumour stage correlate to poor outcome. READ MORE
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22. Hypoxic gene regulation and oncogenic pathways in neuroblastoma
Abstract : Neuroblastoma patients show remarkable clinical heterogeneity, with courses ranging from spontaneous regression to fatal tumor progression despite intense multi-modal treatment. Previous studies have shown that hypoxia pushes neuroblastoma cells towards a more immature phenotype, which correlates to aggressive disease. READ MORE
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23. Approaches to Treatment of Children with Advanced Neuroblastoma
Abstract : Children with advanced neuroblastoma are at high risk for relapse of multidrug resistant disease, despite initial response to intensive multimodality treatment. Neuroblastomas have similarities with immature neuroblasts seen during embryonic development of the sympathetic nervous system (the origin of these tumors). READ MORE
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24. Effects of ellagic acid in human neuroblastoma cells
Abstract : A diet rich in polyphenols has been proposed to have beneficial health effects and to reduce risk of disease. Ellagic acid, a polyphenol common in red berries and pomegranates, has potential anti-tumorigenic effects that make it interesting to further study in different cancer cell systems. READ MORE
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25. Notch Signaling in Neuroblastoma and Renal Cell Carcinoma
Abstract : The Notch signaling pathway governs cell functions essential for normal development and organogenesis. Aberrant Notch signaling has been implicated in tumorigenesis by perturbing control of proliferation, differentiation, apoptosis, migration and angiogenesis. READ MORE