Search for dissertations about: "neurotoxin gene expression"

Found 5 swedish dissertations containing the words neurotoxin gene expression.

2. 1. A Molecular Approach for Investigation of the Prevalence and Neurotoxin Formation of Clostridium botulinum in Food Safety Assessment

   Author : Maria Lövenklev; Teknisk mikrobiologi; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; neurotoxin gene expression; neurotoxin; food safety assessment; food preservation; Clostridium botulinum; enrichment PCR; Food and drink technology; qRT-PCR; Livsmedelsteknik; prevalence;

   Abstract : In the development of new food products, more knowledge is needed about the occurrence and quantity of food-borne pathogens in the food chain to be able to implement effective control measures and assure food safety. In addition, improved understanding of how environmental factors and food preservatives effect the microbial virulence expression in foods will enable the formulation of new strategies for food preservation and risk assessment. READ MORE

4. 2. Structural and functional studies of a novel Botulinum neurotoxin and of MTH1

   Author : Linda Henriksson; Pål Stenmark; Maria Selmer; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Botulinum neurotoxin; botulism; cancer; gene cluster; molecular structures; MTH1; NTNH; oxidised nucleotides; progenitor complex; protein expression; protein purification; X-ray crystallography; Biochemistry; biokemi;

   Abstract : X-ray crystallography visualizes the three dimensional molecular structures of proteins at atomic resolution. Seeing the molecular structure of a biomedically interesting protein enables a higher understanding of its function. READ MORE

5. 3. Real-time PCR for diagnosis of botulism and quantification of neurotoxin gene expression in Clostridium botulinum

   Author : Ingrid Artin; Avdelningen för medicinsk mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; detection; qRT-PCR; Clostridium botulinum; molecular methods;

   Abstract : The objectives of the work presented in this thesis have been to develop molecular methods for (i) detection of Clostridium botulinum in food and clinical samples, and (ii) monitoring the expression of the neurotoxin gene, cnt, during different growth phases and under different growth conditions. For the diagnosis of botulism, a real-time PCR-based method including an internal amplification control for C. READ MORE

6. 4. Intracellular signaling and cellular plasticity in a rat model of L-DOPA-induced dyskinesia

   Author : Jenny Westin; Neurobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein synthesis; Nukleinsyror; proteinsyntes; neurofysiologi; Nucleic acids; Neurologi; neuropsykologi; L-DOPA; Dopamine; Neurology; neuropsychology; neurophysiology; Parkinson s disease;

   Abstract : Parkinson's disease (PD) is a neurodegenerative disorder where the midbrain dopaminergic neurons are lost. Presently there is no cure for PD, and the most common treatment is to replace the lost dopamine pharmacologically by administration of the dopamine precursor L-DOPA. READ MORE

7. 5. Immunocytochemical studies of cutaneous nerves in human normal and prurigo nodularis skin

   Author : Yong Liang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Axon; CGRP; ECP; EDN EPX; eosinophil; histamine; HLA-DR; immunoelectron microscopy; Langerhans cell; mast cell; NSE; nerve fiber; p75 NGFr; PGP 9.5; prurigo nodularis; S-100; Schwann cell;

   Abstract : Cutaneous nerves may regulate the immune system and be involved in inflammatory events of the skin. Prurigo nodularis is a skin disease which histologically reveals a massive neural hyperplasia and a local inflammation in the lesional skin. READ MORE