Search for dissertations about: "nitric oxide brain"

Showing result 1 - 5 of 47 swedish dissertations containing the words nitric oxide brain.

2. 1. Pathophysiology of blood-brain barrier, brain edema and cell injury following hyperthermia : New role of heat shock protein, nitric oxide and carbon monoxide : an experimental study in rat using light and electron microscopy

   Author : Hari Shanker Sharma; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; blood-brain barrier; heat stress; hyperthermia; brain edema; serotonin; nitric oxide; carbon monoxide; heat shock protein; glial fibrillary acidic protein; myelin basic protein; opioids; histamine; catecholamines; naloxone; indomethacin; p-CPA; electron microscopy; immunocytochemistry; Cellbiologi; Cell biology; Cellbiologi; Human Anatomy; anatomi;

   Abstract : This thesis deals with the molecular mechanisms of hyperthermia induced brain damage in rats. The results clearly establish that hyperthermia caused by 4 h heat stress at 38° C is associated with a breakdown of the blood-brain barrier (BBB) permeability which seems to be instrumental in causing brain edema and cell injury. READ MORE

4. 2. Nitric oxide in brain contusion

   Author : Caroline Gahm; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Apoptosis; Colchicine; Dexamethasone; eNOS; human; immunohistochemistry; iNOS; L-NAME; L-NIL; neuronal degeneration; Nimodipine; nitric oxide; NO; nNOS; rat; SPBN; Tirilazad Mesylate; traumatic brain injury;

   Abstract : Trauma to the brain is a leading cause of death and disability. The primary injury initiates a cascade of biochemical reactions in the brain that causes further neuronal damage, a process referred to as secondary brain injury. READ MORE

5. 3. On Brain Oedema

   Author : Mårten Jungner; Anestesiologi och intensivvård; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatic brain injury; brain oedema; fluid therapy; blood-brain barrier;

   Abstract : Traumatic brain injury and bacterial meningitis may at a glance appear as two different disease entities. The host reaction, however, to both trauma and infection involves a strong inflammatory response, with the classical symptomology of rubor, tumor, calor, dolor et functio laesa. READ MORE

6. 4. Caspase-dependent and caspase-independent neuronal injury in the developing brain

   Author : Changlian Zhu; Göteborgs universitet; []
   Keywords : hypoxia ischemia; neonatal; cell death; caspase; apoptosis-inducing factor; brain; apoptosis; autophagy; nitric oxide;

   Abstract : Aims: To investigate the mechanisms of neuronal cell death after hypoxia-ischemia in the developing brain.Methods: Rats or mice were subjected to left common carotid artery ligation plus hypoxia. Animals were sacrificed at certain time points after hypoxia-ischemia. READ MORE

7. 5. Cerebral Protection in Experimental Cardiopulmonary Resuscitation : With Special Reference to the Effects of Methylene Blue

   Author : Adriana Miclescu; Lars Wiklund; Samar Basu; Jo Kramer-Johansen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac arrest; cardiopulmonary resuscitation; reperfusion injury; methylene blue; nitric oxide; nitric oxide synthases; blood-brain barrier; Anaesthetics and intensive care; Anestesiologi och intensivvård; Anestesiologi; Anaesthesiology;

   Abstract : Although survival rates are increasing, brain injury continues to be a leading cause of death after cardiac arrest (CA). Permanent brain damage after CA is determined by limited tolerance to ischemia from CA and cardiopulmonary resuscitation (CPR), as well as the unique cerebral response to reperfusion after return of spontaneous circulation (ROSC). READ MORE