Search for dissertations about: "nociceptive transmission"

Showing result 1 - 5 of 23 swedish dissertations containing the words nociceptive transmission.

2. 1. Plasticity in mice nociceptive spinal circuits -role of cell adhesion molecules

   Author : Jonas Thelin; Neurofysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Long term-potentiation; Cell adhesion molecule; Pain; Somatosensory imprinting; Medicin människa och djur ; Medicine human and vertebrates ; Nociceptive withdrawal reflex; Species differences; Central sensitisation; Mouse strains; Spinal cord;

   Abstract : Introduction: To understand the function of the genes and their products in the pain system, studies will have to deal with complex issues related to intercellular communication, e.g. plasticity in neuronal networks. READ MORE

4. 2. Modulation of pain by immune factors : a study on interferon-g and its receptor in nociceptive transmission

   Author : Kristina S Vikman; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Cytokines; interferon-gamma; dorsal horn; hypersensitivity; nociceptive transmission; pain; GluR1; AMPA receptor; disinhibition; spontaneous activity; primary cell culture; two-compartment model; spinal cord.;

   Abstract : Immune cytokines have been implicated as important neuromodulators, contributing to neuronal plasticity both in the adult and developing nervous system. In addition, they have been assigned a potential role in the generation of pathological pain, which may occur as a severe symptom following disease states in the nervous system. READ MORE

5. 3. Estrogen receptor expression in relation to pain modulation and transmission : experimental studies in rats

   Author : Åsa Amandusson; Anders Blomqvist; Kaj Fried; Ola Hermanson; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical cell biology; Medicinsk cellbiologi; Medical Cell Biology; Medicinsk cellbiologi; MEDICINE;

   Abstract : Estrogens have a remarkably wide range of actions in the mammalian brain. They not only play a pivotal role in reproductive behavior and sexual differentiation, but also contribute to e.g. thermoregulation, feeding, memory, neuronal survival and the perception of somatosensory stimuli. READ MORE

6. 4. Molecular mechanisms of synaptic transmission and plasticity in spinal sensory pathways

   Author : Max Larsson; Neurofysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; neuropsychology; Neurology; electron microscopy; synaptic plasticity; synapse; pain; spinal cord; hyperalgesia; Neurologi; neuropsykologi; neurofysiologi;

   Abstract : An intense, potentially tissue-damaging (noxious) stimulus may lead to enhanced pain sensation of subsequent noxious stimuli (hyperalgesia) and to the perceiving of innocuous stimuli as painful (allodynia). This is thought to result to a large extent from strengthening of synapses established by primary afferent fibers onto spinal cord dorsal horn neurons. READ MORE

7. 5. Synaptic organization of nociceptive relay nuclei in the cat and primate thalamus

   Author : Ann-Charlott Ericson; Per Brodal; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : The fine structure of two thalamic nociceptive relay nuclei, the nucleus submedius (Sm) in the cat, and the posterior region in the owl monkey, was investigated using anatomical tract tracing techniques, immunohistochemical staining for neuroactive substances, and threedimensional reconstructions of synaptic circuitry. Ascending lamina I axons, labeled by anterograde transport of Phaseolus vulgaris leucoagglutinin, gave rise to two different types of termination in Sm: large, compact clusters of numerous boutons were predominant in the dense focus of the terminal field after a tracer injection at the site of nociceptive-specific neurons in lamina I, and boutons-of-passage type terminations were conspicuous in the periphery of a lamina I terminal field in Sm and predominant following a tracer injection at the site of thermoreceptive-specific neurons in lamina I. READ MORE