Search for dissertations about: "non-BRCA1 BRCA2"
Showing result 1 - 5 of 6 swedish dissertations containing the words non-BRCA1 BRCA2.
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1. Gene Expression Profiling of Hereditary Breast Cancer
Abstract : [abstract missing].... READ MORE
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2. Investigation of the genetic basis of familial non-BRCA1/2 breast cancer
Abstract : Breast cancer is the most common female malignancy in the Western world and approximately 510% of all breast cancer cases present with some degree of family history. In the mid-nineties genetic linkage analyses successfully identified two breast cancer predisposing genes, BRCA1 and BRCA2. READ MORE
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3. On the genetics of hereditary breast/ovarian cancer. BRCA1, BRCA2 and beyond
Abstract : Breast cancer is the most common malignancy in women. Most of the breast cancers are sporadic with no apparent inheritance factor but about 5-10% is believed to be caused by an inherited predisposition. Aims: This thesis aimed at defining the BRCA1/2 mutation spectrum of the west Swedish population and specifically to characterize the BRCA1c. READ MORE
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4. Family history and breast cancer susceptibility : clinical and molecular studies
Abstract : Apart from gender, family history is the most important risk factor for breast cancer. In 5-10 % of the cases there is a family history pattern of an autosomal dominant disease and there is also a familial clustering of breast cancer associated with a more modest increased risk of the disease. READ MORE
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5. Genetic characterization of malignant melanoma and breast cancer
Abstract : Malignant melanoma and breast cancer are common malignant diseases characterized by considerable heterogeneity with respect to genetics, histopathology, biology and clinical course. In breast cancer, two major susceptibility genes have been identified, BRCA1 and BRCA2, which account for a significant proportion of high-risk breast cancer families. READ MORE