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Showing result 1 - 5 of 7 swedish dissertations matching the above criteria.

  2. 1. Recurrent Non-Muscle-Invasive Bladder Cancer

    Author : Sigurdur Gudjonsson; Urologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; early instillation; biopsies; biomarkers; recurrence; bladder cancer; non-muscle-invasive; tissue microarray; gene-expression;

    Abstract : A characteristic feature of non-muscle-invasive bladder cancer (NMIBC) is the high risk of recurrent disease after primary treatment. Although only a minority of cases eventually progress to a life-threatening muscle-invasive tumour, it is necessary to conduct long-term follow-up with repeated cystoscopies. READ MORE

  4. 2. Proteomic Analysis of Urinary Bladder Cancer : Aiming for Novel Biomarkers

    Author : Mårten Lindén; Per-Uno Malmström; Ulrika Segersten; Sara Bergström Lind; Lars Egevad; Uppsala universitet; []
    Keywords : urine; APOE; FGB; GAL1; LRG1; POLR1E; SERPINA1; STMN1; TOP2A; biomarker; diagnostic biomarker; prognostic biomarker; predictive biomarker; mass spectrometry; western blot; dot blot; immunohistochemistry; IHC; tissue microarray; TMA; urothelium; antibody; antibody-based; urinblåsecancer; biomarkör; diagnos; prognos; urin; proteomik; masspektrometri; immunohistokemi; antikroppar; Molecular Biology; Molekylärbiologi; Molekylär medicin; Molecular Medicine;

    Abstract : Urinary bladder cancer is a heterogeneous disease appearing in different forms, e.g. non-muscle invasive and muscle invasive. For all variants, the expression of proteins is interesting to analyze for diagnostic, predictive, prognostic and drug targeting purposes, since it reflects the altered gene expression causing the cancer. READ MORE

  5. 3. Metabolic factors and bladder cancer risk and mortality. Studies to approach causal associations and interactions with smoking and genetic variants

    Author : Stanley Teleka; Registerbaserad epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bladder cancer; metabolic factors; Association; Interaction; Blood pressure; BMI; statistical analysis; Mendelian Randomization Analysis;

    Abstract : Urothelial bladder cancer (BC) is one of the most common cancers in developed countries. It has one of the highest recurrence rates among solid tumors, resulting in regular treatment and follow-up, making it one of the most expensive cancers to treat, and a significant public health burden. READ MORE

  6. 4. Effects of BCG-treatment on urinary bladder cancer with focus on nitric oxide

    Author : Tomas Thiel; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Intravesical Bacillus Calmette-Guérin is used as a single agent or adjuvant therapy in the treatment of non-muscle invasive bladder cancer. In spite being one of the most efficient immunological treatments in cancer, BCG for bladder cancer is afflicted with a number of unsolved problems. READ MORE

  7. 5. Potential immunoregulatory role of T and dendritic cells in cancer : Investigations based on transcriptional analysis

    Author : Milad Abolhalaj; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dendritic cells; T cells; head and neck cancer; acute myeloid leukemia; bladder cancer; T cell exhaustion;

    Abstract : Cancer is a complex disease with various genetic and epigenetic driving factors. Cancer cells form a favored microenvironment to sustain their uncontrolled behavior leading to abnormal growth. With standard treatment including chemotherapy, relapse risk is high due to the resistance that cancer cells can develop against chemotherapy agents. READ MORE