Search for dissertations about: "nucleus accumbens core"
Found 5 swedish dissertations containing the words nucleus accumbens core.
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1. Mechanism of action of antipsychotic drugs : focus on the nucleus accumbens and the prefronta cortex : an experimental study
Abstract : Antipsychotic drugs have been classified as typical or atypical. To achieve an effective antipsychotic effect with typical antipsychotic drugs, e.g. haloperidol, a dopamine D2 receptor blockade of about 70% seems necessary. READ MORE
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2. Dopamine receptors in the rat brain
Abstract : Dopamine receptors belong to a large superfamily of G protein-coupled receptors and consist of the D1, D2, D3, D4, and D5 receptors. The D2, D3, and D4 receptors belong to the D2 receptor family which is characterized by having a large third cytoplasmic loop and a short C-terminus projecting into the cytosol, and by inhibiting the enzyme adenylyl cyclase. READ MORE
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3. Effects of joint cocaine and ethanol on the brain opioid systems
Abstract : Concurrent abuse of cocaine and alcohol is common among human addicts, where 85% of all cocaine users have also been shown to meet the criteria for alcohol dependence. Concurrent abuse of cocaine and alcohol is associated with a more severe dependence and a more pronounced abstinence than using either drug alone. READ MORE
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4. The role of the dopamine system in the ability of (-)-OSU6162 to reduce voluntary alcohol drinking and binge-eating in the rat
Abstract : BACKGROUND AND AIMS: The dopamine system is involved in the reinforcing effects of both food and alcohol and is thus a potential treatment target for alcohol use disorder (AUD) and binge-eating disorder (BED). Alcohol use disorder is characterized by difficulties to control alcohol drinking and by drinking despite adverse consequences. READ MORE
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5. Modulation of prefrontal glutamatergic transmission and 'atypicality' of antipsychotic drugs
Abstract : The glutamate hypothesis of schizophrenia suggests a relationship between hypoactive NMDA receptor-mediated glutamatergic transmission and the pathophysiology of schizophrenia. Previous results have demonstrated that atypical (e.g. clozapine, risperidone, and olanzapine), but not typical (e. READ MORE