Search for dissertations about: "number of circulating cells"
Showing result 1 - 5 of 92 swedish dissertations containing the words number of circulating cells.
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1. Immunopathology of the Pancreas in Type 1 Diabetes
Abstract : Type 1 diabetes (T1D) results from a loss of functional insulin-producing pancreatic beta cells. The etiology of T1D is poorly understood, but the detection of infiltrating inflammatory cells in the pancreas and circulating autoantibodies has led to the common notion that an autoimmune process plays a central role in the pathogenesis of the disease. READ MORE
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2. Molecular Analysis of Breast Cancer Transcriptomes, Genomes, and Circulating Tumor DNA
Abstract : Breast cancer is a very heterogeneous disease in terms of clinical characteristics, genetic aberrations and prognosis. In Paper I, we focused on the CD44 molecule that often is aberrantly expressed in breast cancer and is widely used as a marker for cancer stem cells. READ MORE
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3. Regulation of human mast cell development
Abstract : Mast cells are multifunctional effector cells of the immune system and are best known for theirparticipation in allergic reactions. The aim of this thesis was to investigate how the stem cell factor(SCF)-dependent development of mast cells from cord blood can be regulated by different factors, and tostudy how immature mast cells circulating in the blood can be recruited into the tissue. READ MORE
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4. Translational and clinical aspects of pancreatic cancer
Abstract : Pancreatic cancer is a disease with dismal prognosis due to late detection and ineffective treatments. The majority of the patients already have disseminated disease at the time of diagnosis. The only potential curative treatment, surgery, is extensive with high morbidity and non-ignorable mortality. READ MORE
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5. Micropatterning of hyaluronic acid hydrogels for in vitro models
Abstract : The human body consist of a vast number of cells, and jointly, the cells, form tissues and organs. The cells interact and respond to their local microenvironment. READ MORE