Search for dissertations about: "opioid receptors"

Showing result 1 - 5 of 50 swedish dissertations containing the words opioid receptors.

  2. 1. Opioid ligands and receptors of the joint

    Author : Jonas Bergström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Opioid peptides; enkephalin; opioid receptors; joint; primary afferents; synovial lining cells; vascular smooth muscle; arthritis; osteoarthrosis; immunohistochemistry; radioimmunoassay; RTPCR; binding assay;

    Abstract : The aim was to explore the occurrence of an opioid system in joints. Thus, joint tissues from rats with and without arthritis and also from patients with knee osteoarthrosis were investigated by EM, immunohistochemistry, RIA, HPLC, receptor binding assay and RT-PCR. READ MORE

  4. 2. The opioid peptide dynorphin A : Biophysical studies of peptide–receptor and peptide–membrane interactions

    Author : Johannes Björnerås; Lena Mäler; Astrid Gräslund; Scott Prosser; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dynorphin A; opioid receptor; neuropeptide; bicelles; NMR; diffusion; decomposition; Biophysics; biofysik;

    Abstract : The work presented in this thesis concerns the opioid peptide dynorphin A (DynA). DynA functions primarily as a neurotransmitter and belongs to the family of typical opioid peptides. These peptides are a part of the opioid system, together with the opioid receptors, a family of GPCR membrane proteins. READ MORE

  5. 3. Evolution of the Neuropeptide Y and Opioid Systems and their Genomic Regions

    Author : Görel Sundström; Dan Larhammar; Manfred Schartl; Uppsala universitet; []
    Keywords : neuropeptide Y; opioid; evolution; genome duplication; gene duplication; Hox; SCN; IGFBP; MEDICINE; MEDICIN;

    Abstract : Two whole genome duplications (2R) occurred early in vertebrate evolution. By using combined information from phylogenetic analyses and chromosomal location of genes, this thesis delineates the evolutionary history of two receptor-ligand systems that expanded by these large scale events. READ MORE

  6. 4. Sperm Membrane Channels, Receptors and Kinematics : Using boar spermatozoa for drug toxicity screening

    Author : Alejandro Vicente Carrillo; Heriberto Rodríguez-Martínez; Karl-Eric Magnusson; Rudolf Rigler; Vesa Loitto; Stefan Arver; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Plasma membrane; membrane channels; membrane receptors; kinematics; 3Rprinciples; spermatozoa; boar.;

    Abstract : Internal fertilization usually implies that a spermatozoon, with intact attributes for zygote formation, passes all hurdles during its transport through the female genitalia and reaches the oocyte. During this journey, millions to billions of other spermatozoa perish. READ MORE

  7. 5. Opioid and non-opioid activities of the dynorphins

    Author : Zoya Marinova; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Endogenous opioid peptides a-neoendorphin, dynorphin A (Dyn A), dynorphin B (Dyn B) and big dynorphin (Big Dyn) consisting of Dyn A and Dyn B, collectively known as dynorphins are derived from the precursor protein prodynorphin (PDYN). Dynorphins regulate pain processing and memory acquisition and modulate reward induced by intake of addictive substances. READ MORE