Search for dissertations about: "oral Carcinogenesis"

Showing result 1 - 5 of 16 swedish dissertations containing the words oral Carcinogenesis.

2. 1. Human Papilloma Virus, Epstein-Barr Virus, and Herpes Simplex Virus Type-1 in Oral Squamous Cell Carcinomas from Three Populations

   Author : Jamshid Jalouli; Jan-Michaél Hirsch; Tina Dalianis; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HPV; EBV; HSV; Oral Squamous Cell Carcinoma; Leukoplakia; Oral Lichen Planus; Oral Submucuos Fibrosis; Toombak; Betel quid; Snuff; Oncology; Onkologi; Oncology; Onkologi;

   Abstract : Most oral squamous cell carcinoma (OSCC) is believed to develop via a multistep process of cumulative gene damage in epithelial cells. Increasing incidence of OSCC and evidence that traditional risk factors may not be responsible directed us to investigate the prevalence of virus in pre- and malignant samples. READ MORE

4. 2. Associations of sex, anthropometric and reproductive factors with clinicopathological and molecular characteristics of colorectal cancer

   Author : Jenny Brändstedt; Tumörmikromiljö; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; carcinogenesis; MDCS; anthropometrics; risk factors; sex differences; hormonal therapy; beta-catenin; cyclin D1; p53; MSI; KRAS mutation; BRAF mutation;

   Abstract : Colorectal cancer (CRC) is the third most common cancer globally, with approximately 1.2 million new cases every year. The highest incidence rates are seen in developed countries, thereby imposing dietary and lifestyle factors in the etiology of CRC. READ MORE

5. 3. Modeling of multi-step oral carcinogenesis in vitro : assessment of growth, differentiation and apoptosis markers

   Author : Annette Hansson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Organotypic cultures; apoptosis; terminal squamous differentiation; buccal mucosa; cytokeratins; carcinogenesis; p53;

   Abstract : Human oral mucosa, especially the buccal epithelium, is worldwide a common site for cancer. Cancer development frequently results in inactivation of tumor suppressor p53, a central regulator of growth and programmed cell death, and deregulated expression of structural elements like cytokeratins. READ MORE

6. 4. Oral cancer with special reference to virus detection and quantitative gene expression

   Author : Miranda Shojaeian Jalouli; Lars Sand; Jan Hirsch; Torbjörn Ramqvist; Uppsala universitet; []
   Keywords : HPV; EBV; HSV-1; Oral Squamous Cell Carcinoma; Leukoplakia; apopto-sis; cell cycle regulation; intermediate filament proteins.; Medicinsk genetik; Medical Genetics;

   Abstract : Background. Head and neck cancers (HNC) are among the most common malignancies worldwide, and about 90–92% of oral neoplasias are oral squamous cell carcinomas (OSCC). Alcohol and tobacco consumption have been recognized as the main risk factors for OSCC development. READ MORE

7. 5. Predictive and prognostic biomarkers in oral tongue squamous cell carcinoma

   Author : Michael Ryott; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Oral tongue squamous cell carcinoma (OTSCC) is an aggressive disease frequently associated with poor prognosis due to the high risk of regional failure and mortality rates have been practically unchanged in Sweden the last fifty years, despite advancements in both diagnostics and treatment. Today we lack means to assess the biological aggressiveness of each individual tumor which varies largely. READ MORE