Search for dissertations about: "osteoporosis drugs"

Showing result 1 - 5 of 27 swedish dissertations containing the words osteoporosis drugs.

  1. 1. Automatic image analysis for decision support in rheumatoid arthritis and osteoporosis

    Author : Johan Kälvesten; Anders Persson; Torkel Brismar; Glenn Haugeberg; Claes Lundström; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Osteoporosis; rheumatoid arthritis; digital X-ray radiogrammetry; joint space width; bone densitometry;

    Abstract : Low-energy trauma and fragility fractures represent a major public health problem. The societal cost of the fragility fractures that occurred in Sweden 2010 has been estimated at €4 billion.In rheumatoid arthritis (RA), patient outcomes have improved greatly in recent years. READ MORE

  2. 2. Evaluation of Functionalized Biopolymers as a Step Toward Targeted Therapy of Osteoporosis

    Author : Sujit Kootala; Jöns Hilborn; Peter Thomsen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Osteoporosis; Bone regeneration; Biomaterials; Hyaluronic acid; Bisphosphonates; Osteoclasts; Osteoblasts; Growth factors; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry; Kemi med inriktning mot materialkemi; Chemistry with specialization in Materials Chemistry;

    Abstract : The work presented in this thesis focuses on the development of strategies and smart bioactive materials for the treatment of osteoporosis. High and low molecular weight soluble hyaluronic acid-bisphosphonate (HA-BP) derivatives were investigated for their ability to inhibit osteoclasts. READ MORE

  3. 3. Health economics of osteoporosis

    Author : Fredrik Borgström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Economic evaluation; cost-effectiveness; osteoporosis; fracture related costs; quality of life;

    Abstract : Health economics is concerned about how the scarce resources should most efficiently be allocated to maximise the health outcomes. Health economic evaluation is a method for assessing costs and benefits of alternative treatment strategies for allocating resources to assist decisions aiming at improving efficiency. READ MORE

  4. 4. Mesoporous Implants for Localized Controlled Drug Delivery

    Author : Johan Karlsson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; release kinetics; mesoporous titania; biomineralization; drug delivery; Biomedical implants; osseointegration; osteoporosis drugs; nanotopography; stem cells homing;

    Abstract : The use of bone-anchored implants is today a routine treatment for patients with normal regenerative capacity. However, there is an ongoing development within implant research to improve the osseointegration of implants. READ MORE

  5. 5. Immune regulation by selective estrogen receptor modulators

    Author : Angelina I Bernardi; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Endocrinology; Mice; Lasofoxifene; Bazedoxifene; Raloxifene; Estrogen; Osteoporosis; B cells; T cells; Rheumatoid arthritis;

    Abstract : At menopause, the levels of estrogen decline, leading to loss of estrogen-mediated protective effects on bone and an increased risk of osteoporosis. Hormone replacement therapy, containing estrogen, has been used for many years to prevent and treat osteoporosis in postmenopausal women. READ MORE