Search for dissertations about: "outer membrane vesicles CDT"

Found 4 swedish dissertations containing the words outer membrane vesicles CDT.

  2. 1. Outer membrane vesicle-mediated export of virulence factors from Gram-negative bacteria

    Author : Pramod Kumar Rompikuntal; Sun Nyunt Wai; Ann-Beth Jonsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Outer membrane vesicles; CDT; PGN; PrtV; Campylobacter jejuni; Vibrio cholerae; Aggregatibacter actinomycetemcomitans; molekylärbiologi; Molecular Biology;

    Abstract : The Gram-negative, motile bacterium Campylobacter jejuni is a causative agent of food-borne gastroenteritis. Cytolethal distending toxin (CDT) is one of the important virulence factors for C. jejuni pathogenesis. It was not previously known how CDT is released from C. READ MORE

  4. 2. Vesicle-mediated and free soluble delivery of bacterial effector proteins by oral and systemic pathogens

    Author : Bernard Thay; Jan Oscarsson; Mikael Rhen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Periodontitis; Aggregatibacter actinomycetemcomitans; Staphylococcus aureus; membrane vesicles; vesicle-host cell interaction; protein delivery; molekylärbiologi; Molecular Biology;

    Abstract : Periodontitis, the primary cause of tooth-loss worldwide, is a bacterially induced chronic inflammatory disease of the periodontium. It is associated with systemic conditions such as cardiovascular disease (CVD). However, pathogenic mechanisms of periodontitis-associated bacteria that may contribute to the CVD association are unclear. READ MORE

  5. 3. Bacteria and cancer : from toxin delivery to carcinogenesis

    Author : Riccardo Guidi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Epidemiological evidence link certain chronic bacterial infections to a higher risk of cancer development. Induction of an inflammatory circuit and the accumulation of genomic instability are considered mechanisms by which bacteria contribute to malignant transformation. READ MORE

  6. 4. Bacterial genotoxins : an interface between infection and cancer biology

    Author : Laura Levi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Infections contribute to the development of more than 20% of all malignancies in humans. While strong evidence exists for a number of virus-associated cancers, the role of bacterial infections is still poorly appreciated although there are evidences that link chronic bacterial infections to increased risk of certain tumors. READ MORE