Search for dissertations about: "ovarian cancer methylation"

Showing result 1 - 5 of 7 swedish dissertations containing the words ovarian cancer methylation.

  2. 1. SOX11 as a Cancer Biomarker - Expression and Regulatory Studies in B-cell Lymphomas and Ovarian Cancer

    Author : Elin Gustavsson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SOX11; B-cell lymphomas; DNA methylation; cancer biomarkers; ovarian cancer;

    Abstract : It is estimated that one third of all people in Sweden will be diagnosed with cancer during their lifetime. The outcome for a specific patient is related to early and correct diagnosis, and prediction of effective treatment regimens. Biomarkers are molecules that can aid the clinician in such decisions regarding diagnosis, prognosis and therapy. READ MORE

  4. 2. Novel biomarkers associated with histotype and clinical outcome in early-stage ovarian carcinoma

    Author : Hanna Engqvist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian carcinoma; histotype-specific diagnosis and prognosis; molecular biomarker; outcome prediction; integrative analysis;

    Abstract : Ovarian cancer is a collective name for multiple malignancies deriving from or involving the ovary, mainly comprising five histotypes of epithelial origin (clear-cell (CCC), endometrioid (EC), high-grade serous (HGSC), low-grade serous (LGSC), and mucinous carcinomas (MC)) with varying clinical (e.g. READ MORE

  5. 3. Diet and ovarian cancer : a population-based cohort of 60 000 women

    Author : Susanna C Larsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Ovarian cancer represents the fourth leading cause of cancer-related mortality among women in Western countries. Hence, identification of risk factors amenable to modification, such as diet, is of considerable public health relevance as it could provide means for primary prevention of this malignancy. READ MORE

  6. 4. Molecular genetic analysis of human breast cancer

    Author : Catherine M Phelan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Breast cancer accounts for approximately 20% of all female malignancies with hereditary breast cancer being implicated in 5-10% of these cases. Two highly penetrant hereditary breast cancer genes are known; BRCA1 (17q) and BRCA2 (13q), which also confer an increased risk of cancer at other sites. READ MORE

  7. 5. Investigation of the genetic basis of familial non-BRCA1/2 breast cancer

    Author : Paula Maguire; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Familial non-BRCA1 2 breast cancer; linkage analysis; CGH; association study;

    Abstract : Breast cancer is the most common female malignancy in the Western world and approximately 510% of all breast cancer cases present with some degree of family history. In the mid-nineties genetic linkage analyses successfully identified two breast cancer predisposing genes, BRCA1 and BRCA2. READ MORE