Search for dissertations about: "p27"

Showing result 1 - 5 of 37 swedish dissertations containing the word p27.

  2. 1. Predictive markers for tamoxifen response in primary breast cancer

    Author : Maria Stendahl; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; General pathology; Cytologi; onkologi; prognosis; Cytology; oncology; cancerology; predictive marker; p27; cyclin D1; tamoxifen; PR; breast cancer; ER; pathological anatomy; Patologi allmän ; patologisk anatomi;

    Abstract : It is well-known that a majority of breast cancers are hormone-dependent, making endocrine therapy an important adjuvant treatment after surgery. Susceptibility to endocrine treatment is determined by the presence of estrogen receptors (ER) and progesterone receptors (PR) in the tumors. READ MORE

  4. 2. Cell Cycle Regulation in Human Renal Cell Carcinoma

    Author : Ylva Hedberg; Göran Landberg; Börje Ljungberg; Göran Roos; Ulf Bergerheim; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Human Renal Cell Carcinoma; Cell Cycle; G1 S; Protein; Cyclin; p27; pRb; Phosphorylation; Tissue Microarray; Clinical Behaviour; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : ABSTRACTCell cycle regulation in human renal cell carcinomaYlva Hedberg, Departments of Medical Biosciences, Pathology, and Surgical andPerioperative Sciences, Urology Andrology, Umeå University, SwedenDeregulated growth control is a hallmark of neoplasia potentially caused by aberrant expression of cell cycle regulatory proteins. The importance of such aberrations in human renal cell carcinoma (RCC) has not been fully clarified. READ MORE

  5. 3. Interferon-alpha signaling and cell cycle regulation in neuroendocrine tumors of the digestive system

    Author : Yinghua Zhou; Uppsala universitet; []
    Keywords : Medical sciences; interferon-α; carcinoid tumors; interferon regulatory factor; p68; PKR; p21; p27; cell cycle; cyclin-dependent kinase; protein phosphorylation; protein trafficking; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : The prognosis for untreated carcinoid patients is poor and their quality of life is low. IFN-α treatment has shown a response rate of 50-80%, however, the antitumor mechanism has not been elucidated. READ MORE

  6. 4. Life Style, Molecular Pathology, and Breast Cancer Risk

    Author : Signe Borgquist; Malmö Handkirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hormone receptors; Breast cancer; tissue microarray; histopathology; ERβ; tumour proliferation; cyclin D1; p27; HMG-CoA reductas; life style factors; diet; hormone replacement therapy; obesity; endocrine therapy;

    Abstract : The breast cancer diagnosis covers a wide range of tumours with different geno- and phenotypic characteristics. The diversity among studies on life-style factors and their impact on breast cancer risk might be clarified by recognizing breast cancer as a heterogeneous disease. READ MORE

  7. 5. Statins, HMGCR and Breast Cancer

    Author : Olöf Bjarnadottir; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Statins; HMGCR; Cyclin D1; p27; Clinical trial; Gene expressionprofiling; cholesterol-lowering medication;

    Abstract : .... READ MORE