Search for dissertations about: "p38 MAP kinase"
Showing result 1 - 5 of 28 swedish dissertations containing the words p38 MAP kinase.
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1. Signal Transduction in Mast Cell Migration
Abstract : Mast cells are essential effector cells in the immune system as they release several inflammatory mediators. An accumulation of mast cells has been described in inflammatory conditions such as asthma and allergic rhinitis. READ MORE
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2. Regulation and Function of MAP Kinases in PDGF Signaling
Abstract : Platelet-derived growth factor (PDGF) is a family of signaling molecules that stimulates cell growth, survival and migration. PDGF is recognized by specific transmembrane proteins, the PDGF receptors, which relay the signals to the cell activating the Mitogen-activated protein (MAP) kinases and other signaling pathways. READ MORE
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3. Design and Synthesis of Chalcone and Chromone Derivatives as Novel Anticancer Agents
Abstract : This thesis comprises the design and synthesis of chalcone and chromone derivatives and their use in various biological applications, particularly as anticancer agents (targeting proteins associated with cancer pathogenesis) and as potential fluorophores for live-cell imaging. Conveniently, all structures presented were synthesized from commercially available 2 ́-hydroxyacetophenones. READ MORE
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4. Signaling mechanisms underlying neural stem cell differentiation. Implications of BMPs, retinoids, and MAP kinases
Abstract : Introduction: Neural stem cells are proliferating cells, derived from the nervous system with the ability to give rise to neurons, astrocytes, and oligodendrocytes. The molecular events and signaling pathways regulating neural stem cell differentiation are largely unknown. READ MORE
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5. Mechanisms for TGF-β-Mediated Regulation of the Actin Filament System and Apoptosis
Abstract : Transforming growth factor-β (TGF-β) is a member of a large superfamily of cytokines which participate in many different types of cellular processes, such as growth inhibition, cell migration, differentiation, cell adhesion, wound healing and immunosuppression. Alterations of TGF-β superfamily signalling results in several different disorders, including bone disease, vascular disease and cancer. READ MORE