Search for dissertations about: "palladium Heck"

Showing result 1 - 5 of 34 swedish dissertations containing the words palladium Heck.

2. 1. Palladium(II)-Catalysed Heck and Addition Reactions : Exploring Decarboxylative and Desulfitative Processes

   Author : Bobo Skillinghaug; Mats Larhed; Antonio de la Hoz Ayuso; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Palladium; catalysis; palladium II catalysis; synthesis; Heck; carboxylic acid; sulfinic acid; sodium sulfinate; nitrile; styrene; ketone; aryl ketone; electrospray ionization mass spectrometry; density functional theory; microwave heating; continuous flow; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

   Abstract : Palladium complexes have the ability to catalyse cross-coupling of two organic moieties through the formation of transient metal-carbon bonds, thus bringing them closer to each other to facilitate the formation of a new bond. Palladium-catalysed coupling reactions are one of the most important carbon-carbon forming reactions available to organic chemists and many of these reactions rely on the reactivity of aryl-palladium complexes. READ MORE

4. 2. Palladium(II)-Catalyzed Heck Reactions : Domino Reactions, Decarboxylations, Mechanistic Studies & Continuous Flow Applications

   Author : Ashkan Fardost; Mats Larhed; Patrick Guiry; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; palladium II ; dft; reaction mechanisms; esi-ms; heck; decarboxylation; microwave; continuous flow;

   Abstract : This thesis describes research efforts dedicated to the development of palladium(II)-catalyzed oxidative Heck and Heck/Suzuki domino reactions, and the applications of a new microwave heating technology, purpose-built for continuous flow in organic synthesis.Paper I describes the development of a ligand-modulated approach for attaching aryl groups to a chelating vinyl ether. READ MORE

5. 3. New Methods for the Synthesis of 3-Substituted 1-Indanones : A Palladium-Catalyzed Approach

   Author : Anna Arefalk; Anders Hallberg; Mats Larhed; Juan Carlos Carretero; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Heck; palladium; indanone; annulation; microwave heating; triflate; sulfinyl imine; HIV-1 protease inhibitor; Organisk kemi; Organic chemistry; Organisk kemi;

   Abstract : In medicinal chemistry, there is a constant need for new preparative methods, both to make the synthesis process more effective, and to increase the accessibility to a wide variety of compounds. A number of different approaches can be used to attain these goals. READ MORE

6. 4. Selectivity in Palladium- and Enzyme-Catalyzed Reactions : Focusing on Enhancement of Reactivity

   Author : Peter Nilsson; Anders Hallberg; Mats Larhed; Matthias Beller; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Palladium; Heck; PCR; Microwaves; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

   Abstract : Catalysis has a profound impact on all living species on the earth. Nature’s catalysts, the enzymes, have the ability to selectively promote a specific bio-chemical transformation, given the required substrate. READ MORE

7. 5. Palladium-Catalysed Carbon–Carbon Coupling Reactions : Focusing on Microwave Heating, Low Catalyst Concentrations, Aqueous Conditions, Regioselectivity and Medicinal Chemistry Applications

   Author : Riina K Arvela; Mats Larhed; Anders Hallberg; Michael G Organ; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Suzuki coupling; Heck reaction; palladium; microwave heating; water; vinyl ethregioselective; HIV-1 integrase inhibitor; Pharmaceutical chemistry; Farmaceutisk kemi; farmaceutisk biokemi; Pharmaceutical Biochemistry;

   Abstract : It is widely accepted that palladium is one of the most useful catalysts in organic chemistry, and many palladium(0)-catalysed carbon–carbon bond-forming reactions have been developed over the years. In addition, the ever-growing need for more environmentally benign processes in the chemical industry has driven scientists to look for greener options while developing new methodologies for organic synthesis. READ MORE