Search for dissertations about: "pancreatectomy"

Showing result 1 - 5 of 11 swedish dissertations containing the word pancreatectomy.

2. 1. The Tyrosine Kinase GTK : Signal Transduction and Biological Function

   Author : Cecilia Annerén; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Protein tyrosine kinases; GTK; SHB; proliferation; survival; differentiation; β cells; pancreatectomy; cytokines; diabetes; PC12 cells; NGF; streptozotocin; focal adhesion kinase; RAP1; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

   Abstract : Protein tyrosine kinases play an important role in the regulation of various cellular processes such asgrowth, differentiation and survival. GTK, a novel SRC-like cytoplasmic tyrosine kinase, was recently cloned from a mouse insulinoma cell line and the present work was conducted in order to find a biological function of GTK in insulin producing and neuronal cells. READ MORE

4. 2. Glucose metabolism in patients with exocrine pancreatic adenocarcinoma

   Author : Johan Permert; Linköpings universitet; []
   Keywords : endocrine pancreatic function; euglycemic hyperinsulinemic clamp; exocrine pancreatic adenocarcinoma; glucose metabolism; glyccogen synthesis; hyperglycemic clamp; immunohistochemistry; insulin resistance; insulin secretion; in situ hybridization; islet amuyloid polypeptide IAPP ; radioimmunoassay; subtotal pancreatectomy; MEDICINE; MEDICIN;

   Abstract : Carc.inoma of the exocrine pancreas is the fifth leading cause of cancer death in the Western world and the survival rate is one of the lowest for cancers of any site. Pancreatic cancer is characterized by pronounced, early cachexia and frequent metabolic complications. READ MORE

5. 3. Surgical methods in treating pancreatic tumours

   Author : Johanna Wennerblom; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatoduodenectomy; distal pancreatectomy; pancreatogastrostomy; pancreatojejunostomy; postoperative pancreatic fistula; lymph node 8a; palliative surgery;

   Abstract : Background: In patients with pancreatic cancer 15-20% are resectable at the time of diagnosis. Still another 8-20% are found to be unresectable at laparotomy. The optimal intraoperative strategy for this group is not known. Some patients experience early recurrence of the cancer indicating undetected advanced disease at the time of surgery. READ MORE

6. 4. Effects of Pancreatic Surgery : Quality of Life, Cost-effectiveness and Postoperative Results

   Author : Karin Johansen; Bergthor Björnsson; Per Sandström; Linda Lundgren; Jacob Freedman; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic surgery; Minimally invasive surgical procedures; Octogenarians; Surgical outcome; Quality of life; Cost-effectiveness analysis; Qualitative research;

   Abstract : BACKGROUND  Pancreatic operations are large procedures with high rates of complications and other potentially impactful consequences such as diabetes and pancreatic exocrine insufficiency. Due to this, and due to the fact that the operations are often occasioned by periampullary tumours with a poor prognosis, it is important to evaluate how the operations affect patients in terms of postoperative results and quality of life. READ MORE

7. 5. Role of Islet Endothelial Cells in β-cell Function and Growth

   Author : Magnus Johansson; Leif Jansson; Per-Ola Carlsson; Lena Holm; Susan Bonner-Weir; Uppsala universitet; []
   Keywords : Cell biology; Cellbiologi;

   Abstract : The pancreatic islets are collections of endocrine cells, dispersed throughout the pancreas. In adult islets, endocrine cells are closely associated with capillary endothelial cells and receive a high blood perfusion. Transplanted pancreatic islets, on the other hand, have a vascular disturbance, manifested as decreased blood vessel density. READ MORE