Search for dissertations about: "parallell pathways"

Found 3 swedish dissertations containing the words parallell pathways.

2. 1. Folding of the Ribosomal protein S6 : The role of sequence connectivity, overlapping foldons, and parallel pathways

   Author : Ellinor Haglund; Mikael Oliveberg; Neil Ferguson; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein folding; protein stability; two-state folding; S6; chevron plot; transition state; parallell pathways; foldon; two-channel landscape; protein engineering; H D-exchange; Biochemistry; Biokemi; Biochemistry; biokemi;

   Abstract : To investigate how protein folding is affected by sequence connectivity five topological variants of the ribosomal protein S6 were constructed through circular permutation.  In these constructs, the chain connectivity (i.e. the order of secondary-structure elements) is changed without changing the native-state topology. READ MORE

4. 2. Injury-induced activation of vascular smooth muscle cells. Role of specific gene expression and intracellular signalling pathways

   Author : Cecilia Lövdahl; Reumatologi och molekylär skelettbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metalloproteinase; extracellular matrix; ERK1 2 signalling; migration; proliferation; injury; vessel wall; smooth muscle cell; Medicine human and vertebrates ; Medicin människa och djur ;

   Abstract : Migration and proliferation of smooth muscle cells (SMC) are important events in the development of atherosclerosis and restenosis following angioplastic surgery. It is important to gain further knowledge about the mechanisms regulating SMC form and function in order to understand the underlying disease process. READ MORE

5. 3. Pericyte recruitment and functions in vivo. Studies of platelet-derived growth factor-B deficient embryos

   Author : Mats Hellström; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mouse; gene targeting; platelet-derived growth factor; pericyte; vascular smooth muscle; angiogenesis;

   Abstract : A functional vascular system is essential for tissue growth and maintenance, and the circulatory system is therefore the first operational organ of the vertebrate embryo. In conditions of pathological tissue growth, such as tumors, formation of new blood vessels is also required, and it is anticipated that prevention of blood vessel development in those settings might ameliorate the disease progress. READ MORE