Search for dissertations about: "parathyroid tumors"

Showing result 11 - 15 of 17 swedish dissertations containing the words parathyroid tumors.

  2. 11. Genetic and epigenetic mechanisms in primary hyperparathyroidism

    Author : Luqman Sulaiman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by abnormally excessive secretion of parathyroid hormone (PTH) and elevated serum calcium. PHPT patients can develop a wide range of complications affecting many body organs such as the skeleton, kidneys and heart. READ MORE

  4. 12. Multiple endocrine neoplasia type 1 : clinical and molecular characterization

    Author : Bin Tean Teh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEN1; PYGM; loss of heterozygosity; thymic carcinoid; HPT-JT; HRPT2; FIHP; familial acromegaly; tumor suppressor gene.;

    Abstract : This thesis is based on clinicopathologic and genetic studies of MEN1 and MEN1-like syndromes. Linkage to the MENl locus in chromosome 11q13 was confirmed in the largest known MEN1 family and 5 Swedish MEN1 families. An accuracy of >99. READ MORE

  5. 13. Vitamin D and Breast Cancer. Studies on Incidence and Survival

    Author : Linnea Huss; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; risk; prognosis; vitamin D; PTH; calcium; SNP; VDR.;

    Abstract : Previous research has suggested beneficial effects of vitamin D on both breast cancer risk and prognosis. The overall aim of this research project was to investigate associations between vitamin D and breast cancer. The population-based prospective cohort, the Malmö Diet and Cancer Study, recruited 17,034 women in the first half of the 1990s. READ MORE

  6. 14. Functional studies of the multiple endocrine neoplasia type 1 gene

    Author : Lovisa Bylund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEN1; menin; tumor suppressor gene; cancer; RNAi; promoter; expression; cytogenetic; microarray;

    Abstract : The multiple endocrine neoplasia type 1 (MEN1, OMIM 131 100) syndrome is an autosomal dominant trait with a near 100% penetrance and with an estimated prevalence of 2-20/100 000. The syndrome is characterized by neoplasia affecting the parathyroid glands (90-97%), enteropancreatic endocrine tissues (30-80%) and the anterior pituitary gland (15-50%) but tumors arc also found in other, both endocrine and non endocrine tissues. READ MORE

  7. 15. Studies of Autoantibodies in Systemic and Organ-Specific Autoimmune Disease

    Author : Filip Sköldberg; Olle Kämpe; Fredrik Rorsman; Lars Rönnblom; Eva Landgren; Marie Wahren-Herlenius; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; autoantibodies; autoimmune polyendocrine syndrome type 1; cysteine sulfinic acid decarboxylase; histidine decarboxylase; systemic lupus erythematosus; ahnak; CLLD4; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Molekylär medicin; Molecular Medicine;

    Abstract : Systemic lupus erythematosus (SLE) is the prototypic systemic autoimmune disease, whereas autoimmune polyendocrine syndrome type 1 (APS1) is a rare autosomal disorder characterized by combinations of organ-specific autoimmune manifestations including hypoparathyroidism and intestinal dysfunction, and may serve as a model for organ-specific autoimmunity. Autoantibodies directed against proteins expressed in the affected tissues are found in both diseases. READ MORE