Search for dissertations about: "patch-clamp"

Showing result 16 - 20 of 87 swedish dissertations containing the word patch-clamp.

  2. 16. Progesterone metabolites : learning, tolerance, antagonism & metabolism

    Author : Charlotte Öfverman; Inga-Maj Johansson; Torbjörn Bäckström; Esa Korpi; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allopregnanolone; isoallopregnanolone; THDOC; learning; tolerance; antagonism; inhibition; patch clamp; Morris water maze; metabolism; epimerization; Obstetrics and gynaecology; Obstetrik och gynekologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Progesterone metabolites as allopregnanolone, isoallopregnanolone and tetrahydrodeoxy-corticosterone (THDOC) are increased in the luteal phase of the menstrual cycle, throughout pregnancy and during stress. Allopregnanolone and THDOC are neurosteroids with 3α-hydroxy, 5α-configurations and positive modulating effect on the GABAA receptor. READ MORE

  4. 17. The electrophysiological response of medial preoptic neurons to hypoxia and development of a system for patch-clamp measurement with full oxygen control

    Author : Nazanin Bitaraf; Ronnie Lundström; Luleå tekniska universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Medical Engineering for Healthcare; Medicinsk teknik för hälsovård;

    Abstract : A stroke is caused by interruption of the blood supply to the brain. Yearly 15 million people around the globe endure a stroke and the costs and suffering for the people involved and the society are immense. READ MORE

  5. 18. Molecular aspects on voltage-sensor movement

    Author : Amir Broomand; Fredrik Elinder; Guiscard Seebohm; Linköpings universitet; []
    Keywords : Potassium channels; voltage-gated; chemistry; metabolism; physiology; patch-clamp techniques; oocytes; MEDICINE; MEDICIN;

    Abstract : Voltage-gated ion channels are fundamental for electrical signaling in living cells. They are composed of four subunits, each holding six transmembrane helices, S1-S6. Each subunit contains a voltage-sensor domain, S1-S4, and a pore domain, S5-S6. READ MORE

  6. 19. Bridging the gap in translational epilepsy research - A patient brain tissue platform for validating animal data

    Author : Jenny Wickham; Epilepsicentrum; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epilepsy; patch clamp technique; human tissue; Optogenetics; Dentate gyrus; Subiculum; Hippocampus; in vitro;

    Abstract : .... READ MORE

  7. 20. Transducer properties of a mechanoreceptor : an electrophysiological and pharmacological study of the crayfish stretch receptor

    Author : Jiahui Lin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : stretch receptor; Na channels; K channels; local anesthetics; calmodulin antagonist; patch clamp; voltage clamp;

    Abstract : The abdominal stretch receptor organ of the crayfish, an analog to the human muscle spindle, contains one slowly adapting (SA) and one rapidly adapting (RA) receptor neuron. The general aims of this project were to elucidate, in the SA and RA neurons, the participation of voltagegated Na+ and K+ channels in overall transducer process and adaptation, and to study possible blocking agents specific to mechanosensitive (MS) channels. READ MORE