Search for dissertations about: "peptide mass fingerprinting"

Showing result 1 - 5 of 11 swedish dissertations containing the words peptide mass fingerprinting.

  1. 1. Identification and Characterization of Peptides and Proteins using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Magnus Palmblad; Uppsala universitet.; [2002]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Materials science; Peptide; protein; peptide mass fingerprinting; identification; sequencing; protein structure; non-covalent interaction; modification; electrospray ionization; liquid chromatography; capillary electrophoresis; electron capture dissociation; Fourier transform ion cyclotron resonance mass spectrometry; cerebrospinal fluid; amyloid β-peptide; Alzheimer’s disease.; Materialvetenskap; TECHNOLOGY Materials science; TEKNIKVETENSKAP Teknisk materialvetenskap; Molecular Biotechnology; Molekylär bioteknik;

    Abstract : Mass spectrometry has in recent years been established as the standard method for protein identification and characterization in proteomics with excellent intrinsic sensitivity and specificity. Fourier transform ion cyclotron resonance is the mass spectrometric technique that provides the highest resolving power and mass accuracy, increasing the amount of information that can be obtained from complex samples. READ MORE

  2. 2. Mass spectrometry in protein structure analysis

    University dissertation from Stockholm : Karolinska Institutet, Department of Medical Biochemistry and Biophysics

    Author : Andreas Jonsson; Karolinska Institutet.; Karolinska Institutet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Mass spectrometry is an important analytical tool in biological and biochemical research. The speed, accuracy and sensitivity is unmatched by conventional analytical techniques. READ MORE

  3. 3. Sample preparation and mass spectrometry in proteome studies

    University dissertation from Stockholm : Karolinska Institutet, Department of Medical Biochemistry and Biophysics

    Author : Daniel Hirschberg; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Proteome studies aim to link gene to function. Instead of screening for function in a specific protein as in classical protein chemistry, proteins are now screened against a specific phenotype, disease or metabolic state. READ MORE

  4. 4. Lipoproteomics A New Approach to the Identification and Characterization of Proteins in LDL and HDL

    University dissertation from Institutionen för molekylär och klinisk medicin

    Author : Helen Karlsson; Linköpings universitet.; Linköpings universitet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LDL; HDL; Proteomik; Atheroskleros; Masspektrometri; 2-DE; MEDICINE Morphology; cell biology; pathology Pathology Molecular medicine; MEDICIN Morfologi; cellbiologi; patologi Patologi Molekylär medicin;

    Abstract : A proteomic approach was applied to examine the protein composition of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) in humans. LDL and HDL were isolated by density gradient ultracentrifugation, and proteins were separated with twodimensional gel electrophoresis (2-DE) and identified with peptide mass fingerprinting, using matrix-assisted laser desorption/ionization-time of flight mass spectrometry, and with amino acid sequencing using electrospray ionization tandem mass spectrometry. READ MORE

  5. 5. Nanoporous Aluminum Oxide – A Promising Support for Modular Enzyme Reactors

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Marcus Kjellander; Uppsala universitet.; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; nanoporous aluminum oxide; immobilized enzymes; bioreactor; Biokemi; Biochemistry;

    Abstract : Nanoporous alumina is a rather newly characterized material that so far has found limited use in the construction of bioreactors. The material has many advantages compared to conventional immobilization matrices. I have investigated its use in flow-through bioreactors. READ MORE