Search for dissertations about: "phage-display"

Showing result 1 - 5 of 92 swedish dissertations containing the word phage-display.

  2. 1. Selection and design in antibody phage display

    Author : Jonas Persson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; specificity fine-tuning.; phage display; MUC1; automated selection; antigenicity; antibody; affinity maturation;

    Abstract : The immune system is an important part of the physiology of higher organisms. In the immune system antibodies play a key role in neutralizing and clearing potentially lethal threats from the environment. The importance of antibodies in the immune system has made them come to the attention as a tool in chemistry and medicine. READ MORE

  4. 2. Discovery of targets for tumor immunotherapy using phage display technology

    Author : Jesper Tordsson; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; colon cancer; melanoma; tumor immunotherapy; phage display; scFv; Immunologi; serologi; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : This thesis has focused on the development of methods and their applications for the identification of antibodies reactive with tumor associated antigens (TAA). The phage display technology provides a powerful mean to generate antibodies potentially useful for tumor immunotherapy. READ MORE

  5. 3. Using peptide-phage display to capture conditional motif-based interactions

    Author : Gustav Sundell; Ylva Ivarsson; Per Jemth; Attila Reményi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein-protein interaction; PDZ domain; phosphorylation; peptide-phage display; ProP-PD; phospho-peptide; phosphomimetic substitution; Scribble; NMR; DLG1; PTM; affiinity; Biokemi; Biochemistry;

    Abstract : This thesis explores the world of conditional protein-protein interactions using combinatorial peptide-phage display and proteomic peptide-phage display (ProP-PD). Large parts of proteins in the human proteome do not fold in to well-defined structures instead they are intrinsically disordered. READ MORE

  6. 4. Biomolecular recognition : recombinant antibodies, phage display and eukaryotic cloning systems

    Author : Michelle A. Alting-Mees; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  7. 5. Combinatorial Methodology. Screening for affinity specific ligands to biological and artificial receptors

    Author : Margareta Krook; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; peptide library; combinatorial; screening; phage display; affinity; DNA-interaction; chymotrypsin; peptide inhibitor; antibody; IgG; Fc; molecular imprinting; steroid; receptor; Biochemistry; Metabolism; Biokemi; Biotechnology; Bioteknik;

    Abstract : Combinatorial screening methodology has been employed to select new affinity specific ligands to bilogical and artificial receptors. The screening methodology, in particular screening of combinatorial phage display peptide libraries against target molecules differing in function and shape, is focused upon. READ MORE