Search for dissertations about: "pharmacological treatment"

Showing result 1 - 5 of 534 swedish dissertations containing the words pharmacological treatment.

  2. 1. IgA Nephropathy – Mucosal Immunity and Treatment Options

    Author : Hilde Kloster Smerud; Bengt Fellström; Gudjon Kristjansson; Roger Hällgren; Johan W. de Fijter; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IgA nephropathy; mucosal immunity; gastrointestinal sensitivity; food allergens; pharmacological treatment; budesonide; statin; clinical trial; renal transplantation; recurrence; Internal Medicine; Internmedicin;

    Abstract : In the present studies we have explored the link between food hypersensitivity and IgA nephropathy (IgAN) and evaluated treatment options in primary and recurrent disease. Approximately one third of our IgAN patients had a rectal mucosal sensitivity to gluten, as demonstrated by increased local mucosal nitric oxide production and/or myeloperoxidase release after gluten challenge. READ MORE

  4. 2. Irritable bowel syndrome diagnosed in primary care : Occurrence, treatment and impact on everyday life

    Author : Åshild Olsen Faresjö; Ingemar Åkerlind; Ewa Grodzinsky; Toomas Timpka; Gunnel Hensing; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Irritable bowel syndrome IBS ; occurence; treatment; psychosocial factors; psychological factors; working conditions; gender; health-related qualtity of life HRQOL ; Social medicine; Socialmedicin;

    Abstract : Background: IBS is the most common functional gastrointestinal disorders and affects approximately 10-20 % of the general population and is widespread in all societies and socio-economic groups. Although the disorder does not have a life-threatening course, it still seriously affects the patients in their everyday life. READ MORE

  5. 3. Inhaled pharmacological treatment and critical inhaler technique errors in patients with chronic obstructive pulmonary disease

    Author : Johanna Sulku; Elisabet I. Nielsen; Alf Tunsäter; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic obstructive pulmonary disease; COPD; critical inhaler technique error; pharmacological treatment; ICS; inhaled corticosteroid; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease characterised by persistent respiratory symptoms and a high risk of exacerbations. Preventive and maintenance pharmacological treatment is primarily administered through handheld inhalers, which are available in several different device-drug combinations. READ MORE

  6. 4. Towards Pharmacological Treatment of Cystic Fibrosis

    Author : Charlotte Andersson; Aleksander Edelman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; cystic fibrosis; airway epithelium; genotype; CFTR; chloride transport; genistein; phenotype; phenylbutyrate; S-nitrosoglutathione; Cellbiologi; Cell biology; Cellbiologi; entomologi; Entomology;

    Abstract : S-nitrosogluthatione is an endogenous substance, present at decreased levels in the lungs of CF patients and was recently found to induce mature CFTR in airway epithelial CF cell lines. We show that S-nitrosoglutathione in physiological concentrations increases the presence of ΔF508 CFTR in the cell membrane and induces cAMP dependent chloride transport in cystic fibrosis airway epithelial cells. READ MORE

  7. 5. Novel pharmacological treatment alternatives for schizophrenia

    Author : Charlotte Wiker; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Antipsychotic drugs are commonly divided into typical (first generation) and atypical (second generation) antipsychotic drugs. Clinically effective doses of typical antipsychotic drugs generate a striatal dopamine D2 receptor occupancy of about 70 80%, approaching a level that is associated with a high risk of extrapyramidal side effects. READ MORE