Search for dissertations about: "pharmacology management"

Showing result 1 - 5 of 10 swedish dissertations containing the words pharmacology management.

  2. 1. Hazards of Drug Therapy : On the Management of Adverse Drug Reactions: From Signal Detection and Evaluation to Risk Minimization

    Author : Karin Hedenmalm; Marja-Liisa Dahl; Gunnar Alvan; Ellen Vinge; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; adverse drug reactions; spontaneous reporting systems; drug regulation; pharmacovigilance; incidence; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Abstract : Spontaneous reporting systems (SRSs) for adverse drug reactions (ADRs) have been developed as a result of the thalidomide disaster, whereby thousands of children world-wide were born with birth defects. The Swedish Adverse Drug Reactions Advisory Committee was established in 1965. READ MORE

  4. 2. Reproducible Data Analysis in Drug Discovery with Scientific Workflows and the Semantic Web

    Author : Samuel Lampa; Ola Spjuth; Roland Grafström; Konrad Hinsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Reproducibility; Scientific Workflow Management Systems; Workflows; Pipelines; Flow-based programming; Predictive modelling; Semantic Web; Linked Data; Semantic MediaWiki; MediaWiki; RDF; SPARQL; Golang; Reproducerbarhet; Arbetsflödeshanteringssystem; Flödesbaserad programmering; Prediktiv modellering; Semantiska webben; Länkade data; Go; Bioinformatics; Bioinformatik; Pharmacology; Farmakologi;

    Abstract : The pharmaceutical industry is facing a research and development productivity crisis. At the same time we have access to more biological data than ever from recent advancements in high-throughput experimental methods. READ MORE

  5. 3. Management of chemical risk through occupational exposure limits

    Author : Linda Schenk; Christina Rudén; Michael Gilek; Maria Albin; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; occupational exposure limit; risk assessment; risk management; chemicals regulation; regulatory toxicology; European Union; Toxicology; Toxikologi;

    Abstract : Occupational Exposure Limits (OELs) are used as an important regulatory instrument to protect workers’ health from adverse effects of chemical exposures. The OELs mirror the outcome of the risk assessment and risk management performed by the standard setting actor. READ MORE

  6. 4. Chronic pain : from the study of student attitudes and preferences to the in vitro investigation of a novel treatment strategy

    Author : Linda Rankin; Christopher J. Fowler; Gisselle Gallego; Sofia Mattsson; Emmanuel Bäckryd; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HC-PAIRS; best-worst scaling; palmitoylethanolamine; N-acylthanolamines; oral lichen planus; prostaglandins; chronic pain; prolonged pain; chronic pain education; chronic pain management; medical students; attitudes;

    Abstract : Chronic pain will affect one in five adults during their lifetime, and it exerts a heavy burden on society with major physiological, psychological, social, and economic impacts. The current chronic pain curriculum taught to medical students in most settings is fragmented, inconsistent and inadequate and a vast majority of general practitioners considered their undergraduate training in chronic pain incomplete. READ MORE

  7. 5. Ligand-based Methods for Data Management and Modelling

    Author : Jonathan Alvarsson; Jarl E. S. Wikberg; Ola Spjuth; Claes Andersson; Martin Eklund; John P. Overington; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; QSAR; ligand-based drug discovery; bioclipse; information system; cheminformatics; bioinformatics; Farmaceutisk farmakologi; Pharmaceutical Pharmacology; Bioinformatik; Bioinformatics;

    Abstract : Drug discovery is a complicated and expensive process in the billion dollar range. One way of making the drug development process more efficient is better information handling, modelling and visualisation. The majority of todays drugs are small molecules, which interact with drug targets to cause an effect. READ MORE