Search for dissertations about: "phenotypes"

Showing result 1 - 5 of 712 swedish dissertations containing the word phenotypes.

  2. 1. Mutational effects on protein structure and function

    Author : Jonas Carlsson; Persson Bengt; Uwe Sauer; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mutation; prediction; phenotypes; homology model; virtual screening; molecular dynamics; amyloid; cancer; membrane protein; Bioinformatics; Bioinformatik;

    Abstract : In this thesis several important proteins are investigated from a structural perspective. Some of the proteins are disease related while other have important but not completely characterised functions. READ MORE

  4. 2. Clinical and genetical aspects of Celiac Disease

    Author : Audur Gudjonsdottir; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; celiac disease; sib-pair; screening; genome-wide scan; linkage analysis; heritability; genotypes; DQ2-negative; phenotypes; autoimmune disease;

    Abstract : Celiac disease (CD), or gluten-sensitive enteropathy, is one of the most common chronic diseases in childhood but is diagnosed in all ages. CD is a genetically driven immunological intolerance to dietary gluten. Th e treatment is a gluten-free diet. READ MORE

  5. 3. Trinucleotide repeats and neuropsychiatric phenotypes

    Author : Qiu-Ping Yuan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Trinucleotide; repeat expansion; psychiatric disorder; gene; spastic paraplegia;

    Abstract : Genetic studies of affective disorders have yielded several chromosomal regions suggestive for linkage. Linkage analysis was performed in five families with unipolar affective disorder, collected from northern Sweden. Four candidate regions on chromosomes 16, 18, 21 and 4p were excluded. READ MORE

  6. 4. Inflamed Depression - Origin, Essence, and Remedies

    Author : Klara Suneson; Lund Psykiatri; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Depression; Inflammation; Omega-3 fatty acids; Kynurenine pathway; Phenotypes; Selective serotonin reuptake inhibitor SSRI ;

    Abstract : .... READ MORE

  7. 5. Genetic Variability in Human Bone Phenotypes : The Vitamin D Receptor Gene and the Estrogen Receptor-α Cofactor RIZ Gene

    Author : Elin Grundberg; Andreas Kindmark; Östen Ljunggren; Helena Brändström; André G. Uitterlinden; Uppsala universitet; []
    Keywords : Medicine; Bone mineral density; candidate gene approach; polymorphism; the vitamin D receptor; the estrogen receptor α; RIZ1; cofactor; allelic imbalance; Medicin;

    Abstract : Important candidate genes to human bone phenotypes are those involved in the regulation of hormonal action, such as the vitamin D receptor (VDR) and the estrogen receptor-α (ERα) genes and their cofactors. RIZ1 is a specific ERα cofactor proved to strongly enhance the function of the ERα. READ MORE